Graphene oxide in the water environment could affect tetracycline-antibiotic resistance
Graphene oxide in the water environment could affect tetracycline-antibiotic resistance
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DOI：
10.1016/j.chemosphere.2017.04.145
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发表时间：
2017-09-01
期刊：
影响因子：
8.8
通讯作者：
Zhang, Guo-Sheng
中科院分区：
文献类型：
--
作者：
Guo, Mei-Ting;Zhang, Guo-Sheng
In recent years, the influence of new materials like nanoparticles in the water environment on biological substances has been widely studied. Antibiotic resistance genes (ARGs) represent a new type of pollutant in the environment. Graphene oxide (GO), as a nano material, because of its unique structure, may have an impact on antibiotic resistance bacteria (ARB) and ARGs; however the research in this area is rarely reported. Therefore, this study mainly investigated the effects of GO on bacterial antibiotic resistance. The results showed that GO had a limited effect on ARB inactivation. A high concentration of GO (> 10 mg/L) can damage resistant plasmids to reduce bacterial resistance to antibiotics, but low concentrations of GO (< 1 mg/L) led to almost no damage to the plasmid. However, all tested concentrations of GO promoted the conjugative transfer from 1to over 3 folds, with low concentrations and high concentration (1-10 and 100 mg/L) of GO samples the least promoted. The overall effect of GO on antibiotic resistance needs further investigation. (c) 2017 Published by Elsevier Ltd.
