Effects of Exercise on the Coronary and Collateral Vasculature of Beagles with and without Coronary Occlusion
Effects of Exercise on the Coronary and Collateral Vasculature of Beagles with and without Coronary Occlusion
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运动对有或没有冠状动脉闭塞的比格犬冠状动脉和侧支血管的影响
DOI：
10.1161/01.res.48.4.523
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发表时间：
1981
影响因子：
20.1
通讯作者：
Jack L. WlLSON
中科院分区：
文献类型：
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作者：
K. Scheel;L. Ingram;Jack L. WlLSON
本研究的目的是确定运动是否刺激冠状动脉侧支血管生长，以及冠状动脉闭塞后运动是否能促进额外的侧支血管生长。一组10只比格犬作为对照。第二组由10只正常比格犬组成，每周7天，以最大O2消耗量的50%运动6周。第三组，8只比格犬的回旋支阻断（Ameroid方法）5个月。在第四组中，7只比格犬在回旋支闭塞3个月后进行8周的运动。冠状动脉和侧支循环进行了评估，使用一个孤立的心脏准备。结果发现，运动不会刺激正常比格犬的侧枝生长。然而，与仅冠状动脉闭塞的动物相比，冠状动脉闭塞后的运动使受损血管床的侧支传导增加了一倍。我们的研究表明，在冠状动脉闭塞的比格犬中，经过3个月的恢复期后，运动可以促进心外膜和心肌内（隔膜！）抵押增长经过训练的动物的冠状动脉储备恢复到初始容量的52%，而未经训练的动物为34%。CircRes 48：523- 530，1981
The purpose of this study was to determine if exercise stimulates coronary collateral vessel growth and if exercise after coronary occlusion can promote additional collateral growth. One group of 10 beagles served as control. The second group consisted of 10 normal beagles exercised at 50% of maximum O2 consumption 7 days/week for 6 weeks. In the third group, the circumflex was occluded (Ameroid method) in eight beagles for 5 months. In the fourth group, seven beagles were exercised for 8 weeks following 3 months of circumflex occlusion. The coronary and collateral circulation was assessed, using an isolated heart preparation. It was found that exercise did not stimulate collateral growth in normal beagles. However, exercise after coronary occlusion doubled collateral conductance to the impaired vascular bed compared to animals with only coronary occlusion. Our study shows that, in beagles with coronary occlusion, exercise after a 3-month convalescent period promotes epicardial and intramyocardial (septa!) collateral growth. Coronary reserve in the trained animals returned to 52% of initial capacity vs. 34% for the untrained animals. Circ Res 48: 523-530,1981
20世纪80年代以来家庭消费和资产的实证分析
DOI：
--
发表时间：
2006
期刊：
総務省統計研修所 リサーチペーパー 第5号
影响因子：
--
作者：
元山 斉;山口 幸三;ryoko Morozumi;美添泰人・荒木万寿夫
通讯作者：
美添泰人・荒木万寿夫