Intra-operative specimen analysis using faxitron microradiography for excision of mammographically suspicious, non-palpable breast lesions.

Intra-operative specimen analysis using faxitron microradiography for excision of mammographically suspicious, non-palpable breast lesions.
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使用faxitron显微放射成像技术进行术中标本分析,以切除乳房X线检查可疑的、不可触及的乳腺病变。

DOI:
10.1016/j.breast.2004.02.005
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发表时间:
2004
期刊:
影响因子:
3.9
通讯作者:
H. Sinnett
H. Sinnett
中科院分区:
医学2区
文献类型:
--
作者:
M. Muttalib;L. Tisdall;R. Scawn;S. Shousha;R. Cummins;H. Sinnett

文献摘要

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数字成像的最新进展使得Faxitron显微放射照相成为术中常规标本放射照相(CSR)的有吸引力的替代方法,用于切除线定位的乳房病变。在一项非随机研究中,我们评估了Faxitron标本分析时间、数字图像处理的有效性和再次切除率,并与CSR进行了对比。在299例针对乳腺x线摄影可疑的不可触及乳腺病变的连续线定位切除中(Faxitron为172例,CSR为127例)。两组平均手术时间分别为34.7 min和42.7min,再切除率分别为19.8%和31.5% (χ2分析P<0.1,差异无统计学意义)。Faxitron数字图像处理导致50%(60/121)的癌症切除进行腔活检。其中19例(16%)的组织学切除缘由不完整变为完整。更短的Faxitron平均操作时间使每个剧院列表的额外线路本地化操作成为可能。数字成像指导外科医生进行额外的腔活检,导致再切除率与CSR一样好。
Recent advances in digital imaging have made Faxitron microradiography an attractive alternative to intra-operative conventional specimen radiography (CSR) for the excision of wire-localized breast lesions. Faxitron specimen analysis time, usefulness of digital image manipulation and re-excision rates were evaluated in comparison to CSR in 299 consecutive wire-localized excisions for mammographically suspicious non-palpable breast lesions (172 procedures with Faxitron, 127 with CSR) in a non-randomized study. The corresponding mean operation times were 34.7 vs. 42.7min and the respective re-excision rates were 19.8% vs. 31.5% (no significant difference on χ2analysis P<0.1). Faxitron digital image manipulation led to cavity biopsies in 50% (60/121) of the cancer excisions. In 19 of these (16%), histological excision margins were converted from incomplete to complete. The shorter Faxitron mean operating time enables an additional wire-localized operation per theatre list. Digital imaging guides the surgeon for additional cavity biopsies, resulting in re-excision rates as good as CSR.