Glucose and Insulin Tolerance Tests in the Mouse
Glucose and Insulin Tolerance Tests in the Mouse
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DOI：
10.1007/978-1-4939-2929-0_17
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发表时间：
2015-01-01
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影响因子：
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通讯作者：
Gonzalez-Navarro, Herminia
中科院分区：
文献类型：
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作者：
Vinue, Angela;Gonzalez-Navarro, Herminia
体内代谢测试对于确定小鼠模型中的动脉粥样硬化进展是否伴随碳水化合物代谢改变（例如葡萄糖不耐受和胰岛素抵抗）非常有价值。在本章中，我们描述了在小鼠葡萄糖和胰岛素耐量测试中执行的方案，这两种代谢测定分别评估葡萄糖耐量和胰岛素敏感性。
In vivo metabolic tests are highly valuable to determine whether atherosclerosis progression in mouse models is accompanied by carbohydrate metabolism alterations such as glucose intolerance and insulin resistance. In this chapter, we describe protocols to perform in the mouse glucose and insulin tolerance tests, two metabolic assays which evaluate the glucose tolerance and the insulin sensitivity, respectively.