The Prevalence of Glaucoma in Adult Rural Chinese Populations of the Bai Nationality in Dali: The Yunnan Minority Eye Study

The Prevalence of Glaucoma in Adult Rural Chinese Populations of the Bai Nationality in Dali: The Yunnan Minority Eye Study
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大理白族农村成人青光眼患病率:云南少数民族眼科研究

DOI:
10.1167/iovs.11-9306
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发表时间:
2012-05-01
影响因子:
4.4
通讯作者:
Yuan, Yuansheng
Yuan, Yuansheng
中科院分区:
医学2区
文献类型:
--
作者:
Zhong, Hua;Li, Jun;Yuan, Yuansheng

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目的。我们评估了中国农村白族人群青光眼的患病率。方法:在中国西南地区随机抽取50岁的白族人群进行以人群为基础的调查。符合条件的人被邀请到当地的考点进行全面的眼科检查。结果:在这项研究中,2133名受试者(参与率为77.8%)被检查,所有青光眼的粗略患病率为2.2%(95%可信区间为1.6%-2.9%)。原发性开角型青光眼(POAG)占1.0%(95%CI 0.6%~1.6%),原发性闭角型青光眼(PACG)占0.9%(95%CI 0.6%~1.4%)。所有青光眼的患病率在老年人和女性中明显更高。平均眼压为16.17±3.74 mm Hg(分别为97.5和99.5百分位数,24 mm Hg和30 mm Hg)。平均垂直杯盘比(VCDR)为0.43+/-0.17(分别为97.5和99.5个百分位数0.7和0.8)。青光眼的单盲患病率为80%,而青光眼的患病率仅为36.3%。结论:青壮年的患病率与中国西南部农村白族人群中的青光眼患病率相似。与POAG相比,PACG的视力损害和预后更差。(投资眼科VS科学。地址:10.1167/iovs.11-9306
PURPOSE. We evaluated the prevalence of glaucoma in adults of the Bai Nationality populations in rural China.METHODS. A population-based survey of Chinese Bai Nationality aged >= 50 years from randomly selected block groups in southwestern China was conducted. Eligible persons were invited to local examination sites for a complete ophthalmic examination. Glaucoma was diagnosed using the International Society of Geographical and Epidemiological Ophthalmology Classification scheme.RESULTS. In the study, 2133 subjects (77.8% participation rate) were examined, with a crude prevalence of all glaucoma of 2.2% (95% confidence interval [CI] 1.6%-2.9%). Primary open angle glaucoma (POAG) was found in 1.0% of cases (95% CI 0.6%-1.6%) and primary angle-closure glaucoma (PACG) in 0.9% (95% CI 0.6%-1.4%). The prevalence of all glaucoma was significantly higher in older people and women. Mean intraocular pressure (IOP) was 16.17 +/- 3.74 mm Hg (97.5th and 99.5th percentiles, 24 mm Hg and 30 mm Hg, respectively). The mean vertical cup-to-disc ratio (VCDR) was 0.43 +/- 0.17 (97.5th and 99.5th percentiles 0.7 and 0.8, respectively). Unilateral blindness was found in 80% of PACG, compared to only 36.3% of POAG cases.CONCLUSIONS. Prevalence of POAG is similar to PACG in the ethnic Bai population living in rural southwestern China. PACG has a worse visual impairment and prognosis compared to POAG. (Invest Ophthalmol Vis Sci. 2012;53:3221-3225) DOI:10.1167/iovs.11-9306