A new naphthoquinoneimine derivative from the marine algal-derived endophytic fungus Aspergillus niger EN-13

A new naphthoquinoneimine derivative from the marine algal-derived endophytic fungus Aspergillus niger EN-13
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来自海洋藻类内生真菌黑曲霉 EN-13 的新型萘醌亚胺衍生物

DOI:
10.1016/j.cclet.2007.05.054
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发表时间:
2007-08-01
影响因子:
9.1
通讯作者:
Wang, Bin Gui
Wang, Bin Gui
中科院分区:
化学1区
文献类型:
--
作者:
Zhang, Yi;Li, Xiao Ming;Wang, Bin Gui

文献摘要

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从海洋棕色真菌Colpomenia sinuosa的内部组织中分离到一株内生真菌Aspergillus尼日尔EN-13,经培养鉴定得到一个新的萘醌亚胺衍生物,即5,7-二羟基-2-[1-(4-甲氧基-6-氧代-6H-吡喃-2-基)-2-苯乙胺基]-[1,4]萘醌。通过2D NMR、EI-MS、HR-ESI-MS等波谱分析,确定了新化合物的结构,并初步证实了其具有一定的抗真菌活性。(c)2007年王斌贵。Elsevier B. V.代表中国化学会出版。All rights reserved.
Cultivation of an endophytic fungus Aspergillus niger EN-13 that was isolated from the inner tissue of the marine brown alga Colpomenia sinuosa resulted in the characterization of a new naphthoquinoneimine derivative, namely, 5,7-dihydroxy-2-[1-(4methoxy-6-oxo-6H-pyran-2-yl)-2-phenylethylaniino]-[1,4]naphthoquinone. The structure of the new compound was established on the basis of various NMR spectroscopic analyses including 2D NMR techniques, EI-MS, and HR-ESI-MS. This compound displayed moderate antifungal activity. (c) 2007 Bin Gui Wang. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.