Similar multimorbidity patterns in primary care patients from two European regions: results of a factor analysis.
Similar multimorbidity patterns in primary care patients from two European regions: results of a factor analysis.
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DOI：
10.1371/journal.pone.0100375
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发表时间：
2014
期刊：
影响因子：
3.7
通讯作者：
Prados-Torres A
中科院分区：
文献类型：
--
作者：
Poblador-Plou B;van den Akker M;Vos R;Calderón-Larrañaga A;Metsemakers J;Prados-Torres A
使用经验证的方法，比较两个欧洲地区（西班牙和荷兰）初级保健系统具有相似组织特征的初级保健患者中确定的多死亡模式之间的相似性。这项观察性、回顾性、多中心研究分析了来自初级保健电子病历的信息。对14岁以上患者的诊断信息进行探索性因素分析，评估多发病模式。分析按年龄组和性别分层。对荷兰数据的分析表明，多发性硬化症的发病率较高，这与每种模式中聚集的疾病数量较多相对应。相关的临床相似性，发现这两个国家之间的三个多发病模式，以前确定在最初的西班牙研究：心脏代谢，机械和精神药物滥用。此外，随着年龄的增长，心脏代谢模式向复杂性的临床演变-已经在原始研究中得到证实-在荷兰的背景下得到证实。机械和心理社会障碍之间的明确关联是荷兰人口所独有的，以及在所有年龄和性别群体中反复出现的精神药物滥用模式。从两个不同的欧洲国家的初级保健患者的心脏代谢，机械和精神药物滥用模式的相似性，可以提供初步的线索，制定临床实践指南，如果在其他情况下进一步证明。这项研究也赞同使用初级保健电子病历的流行病学特征的多发病。
To compare the similarities among the multimorbidity patterns identified in primary care patients from two European regions (Spain and the Netherlands) with similar organisational features of their primary care systems, using validated methodologies. This observational, retrospective, multicentre study analysed information from primary care electronic medical records. Multimorbidity patterns were assessed using exploratory factor analysis of the diagnostic information of patients over 14 years of age. The analysis was stratified by age groups and sex. The analysis of Dutch data revealed a higher prevalence of multimorbidity which corresponds with the clustering of a higher number of diseases in each of the patterns. Relevant clinical similarities were found between both countries for three multimorbidity patterns that were previously identified in the original Spanish study: cardiometabolic, mechanical and psychiatric-substance abuse. In addition, the clinical evolution towards complexity of the cardiometabolic pattern with advancing age -already demonstrated in the original study- was corroborated in the Dutch context. A clear association between mechanical and psychosocial disorders was unique to the Dutch population, as well as the recurrent presentation of the psychiatric-substance abuse pattern in all age and sex groups. The similarities found for the cardiometabolic, mechanical and psychiatric-substance abuse patterns in primary care patients from two different European countries could offer initial clues for the elaboration of clinical practice guidelines, if further evidenced in other contexts. This study also endorses the use of primary care electronic medical records for the epidemiologic characterization of multimorbidity.
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影响因子：
3.7
作者：
Prados-Torres A;Poblador-Plou B;Calderón-Larrañaga A;Gimeno-Feliu LA;González-Rubio F;Poncel-Falcó A;Sicras-Mainar A;Alcalá-Nalvaiz JT
通讯作者：
Alcalá-Nalvaiz JT
影响因子：
3.7
作者：
Islam, M. Mofizul;Valderas, Jose M.;McRae, Ian S.
通讯作者：
McRae, Ian S.
影响因子：
5.9
作者：
Salisbury, Chris;Johnson, Leigh;Montgomery, Alan A.
通讯作者：
Montgomery, Alan A.
影响因子：
2.2
作者：
Stewart, Moira;Fortin, Martin;Maddocks, Heather L.
通讯作者：
Maddocks, Heather L.
影响因子：
4.5
作者：
van den Bussche H;Koller D;Kolonko T;Hansen H;Wegscheider K;Glaeske G;von Leitner EC;Schäfer I;Schön G
通讯作者：
Schön G