PMWS: experimental model and co-infections
PMWS: experimental model and co-infections
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DOI：
10.1016/j.vetmic.2003.10.009
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发表时间：
2004-02-04
影响因子：
3.3
通讯作者：
Charreyre, C
中科院分区：
文献类型：
--
作者：
Allan, GM;McNeilly, F;Charreyre, C
猪圆环病毒2型（PCV2）现在被认为是猪多系统衰竭综合征（PMWS）的病原体，PMWS是一种经济上重要的幼猪衰竭性疾病[J.Vet.Diagn.Invest. 12（2000）3]。PMWS的大体病变包括全身性淋巴结病、肝炎、肾炎和肺炎，典型的组织学病变包括淋巴结内淋巴细胞减少和多核巨细胞形成、肝细胞变性和坏死以及多灶性淋巴组织细胞性间质性肺炎。本文将综述本研究组内无菌（GN）、初乳剥夺（CD）和初乳喂养（CF）猪的实验感染结果。和其他地方，与PCV 2和结论，可以从这项工作中得出。(C)2003 Elsevier B.V.保留所有权利。
Porcine circovirus type 2 (PCV2) is now recognised as the causal agent of porcine multisystemic wasting syndrome (PMWS), an economically important wasting disease of young pigs [J. Vet. Diagn. Invest. 12 (2000) 3]. Gross lesions of PMWS include generalised lymphadenopathy, hepatitis, nephritis and pneumonia and typical histological lesions include lymphocytic depletion and multinucleated giant cell formation in lymph nodes, degeneration and necrosis of hepatocytes, and multifocal lymphohistocytic interstitial pneumonia.This communication will review the results of experimental infections of gnotobiotic (GN), colostrum-deprived (CD) and colostrum-fed (CF) pigs within our group, and elsewhere, with PCV2 and the conclusions that can be drawn from this work. (C) 2003 Elsevier B.V. All rights reserved.