High-Resolution Three-Dimensional Contrast-Enhanced Blood Oxygenation Level-Dependent Magnetic Resonance Venography of Brain Tumors at 3 Tesla: First Clinical Experience and Comparison with 1.5 Tesla

High-Resolution Three-Dimensional Contrast-Enhanced Blood Oxygenation Level-Dependent Magnetic Resonance Venography of Brain Tumors at 3 Tesla: First Clinical Experience and Comparison with 1.5 Tesla
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3 特斯拉脑肿瘤高分辨率三维对比增强血氧水平依赖性磁共振静脉造影:首次临床经验以及与 1.5 特斯拉的比较

DOI:
10.1097/01.rli.0000069790.89435.e7
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发表时间:
2003
影响因子:
6.7
通讯作者:
S. Trattnig
S. Trattnig
中科院分区:
医学1区
文献类型:
--
作者:
M. Barth;I. Nöbauer;J. Reichenbach;V. Mlynárik;A. Schöggl;C. Matula;S. Trattnig

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目的评价高分辨率3D对比增强血氧水平依赖性磁共振静脉造影(CE-MRV)在3特斯拉(T)和1.5特斯拉(T)下诊断原发性脑肿瘤和转移瘤的临床潜力。方法应用标准剂量的MRI对比剂(0.1 mmol/kg gadodiamide)对18例脑肿瘤患者进行CE-MRV检查。CE-MRV基于高分辨率3D血流补偿梯度回波序列,回声时间长,利用对比度增强的血氧水平依赖效应。该技术在执行标准成像序列后,在两种场强下使用相同的体积覆盖和采集时间。结果与1.5 T相比,3 T时CE-MRV具有更高的空间分辨率,可显示更多肿瘤内部和周围的细节。与标准成像方案相比,3 T时更强的敏感性加权和更高的本征信噪比增强了可见性,CE-MRV图像在病变内部或周围发现了更多以管状和非管状低信号结构为特征的信息。结论与1.5 T相比,在相同的测量时间和相同的体积覆盖范围内,3 T的CE-MRV数据可以提高空间分辨率,从而提供更详细的信息。该方法也可能显示出估计肿瘤供氧的潜力,特别是在高场强下。
Rationale and ObjectivesTo evaluate the clinical potential of high-resolution 3D contrast-enhanced blood oxygenation level-dependent MR-Venography (CE-MRV) for primary brain tumors and metastases at 3 Tesla (T) in comparison to 1.5 T. MethodsEighteen patients with brain tumors were examined using CE-MRV after application of a standard dose of MRI contrast agent (0.1 mmol/kg gadodiamide). CE-MRV is based on a high-resolution 3D flow-compensated gradient-echo sequence with long echo times that uses the contrast-enhanced blood oxygenation level-dependent effect. This technique was performed using the same volume coverage and acquisition time at both field strengths after performing standard imaging sequences. ResultsThe higher spatial resolution of CE-MRV at 3 T showed more details within and around tumors than at 1.5 T. Visibility was enhanced by stronger susceptibility weighting and higher intrinsic signal-to-noise at 3 T. Compared with standard imaging protocols, additional information characterized as tubular and nontubular hypointense structures were found within or around lesions on CE-MRV images. ConclusionsAcquisition of CE-MRV data at 3 T enables spatial resolution to be increased within the same measurement time and with the same volume coverage compared with 1.5 T, thus providing more detailed information. The method may also show the potential to estimate oxygen supply of tumors, especially at high field strengths.
8 特斯拉 MRI 的颅内骨化和微血管病。
DOI: 10.1016/s0730-725x(01)00447-7
发表时间: 2001
影响因子: 2.5
作者:
Novak,V;Abduljalil,A;Kangarlu,A;Slivka,A;Bourekas,E;Novak,P;Chakeres,D;Robitaille,PM
通讯作者: Robitaille,PM
接受治疗的神经胶质瘤患者的相对脑血容量和质子能谱的比较。
DOI: --
发表时间: 2000
期刊: AJNR. American journal of neuroradiology
影响因子: --
作者:
Henry,RG;Vigneron,DB;Fischbein,NJ;Grant,PE;Day,MR;Noworolski,SM;Star-Lack,JM;Wald,LL;Dillon,WP;Chang,SM;Nelson,SJ
通讯作者: Nelson,SJ