Palladium-catalyzed intermolecular coupling of aryl chlorides and sulfonamides under microwave irradiation
Palladium-catalyzed intermolecular coupling of aryl chlorides and sulfonamides under microwave irradiation
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DOI：
10.1021/ol035655u
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发表时间：
2003-11-13
期刊：
影响因子：
5.2
通讯作者：
Rivero, R
中科院分区：
文献类型：
--
作者：
Burton, G;Cao, P;Rivero, R
采用钯催化剂实现了磺酰胺与芳基氯的分子间N-芳基化反应。反应在微波辐射下在180-200 ℃下进行10分钟，使用2-10摩尔%的Pd催化剂，分离产率为32-85%。
An efficient intermolecular N-arylation of sulfonamides with aryl chlorides is realized using palladium catalysis. The reaction proceeds under microwave irradiation at 180-200 degreesC for 10 min with 2-10 mol % of Pd catalyst in 32-85% isolated yields.