Development of the new lung allocation system in the United States
Development of the new lung allocation system in the United States
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DOI：
10.1111/j.1600-6143.2006.01276.x
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发表时间：
2006-05-01
影响因子：
8.8
通讯作者：
Grover, FL
中科院分区：
文献类型：
--
作者：
Egan, TM;Murray, S;Grover, FL
本文回顾了2005年春季生效的新的美国肺分配系统的发展。1998年，美国卫生与公众服务部卫生资源和服务管理局发布了《器官采购和移植网络最终规则》。根据2000年生效的这一规则，被占领巴勒斯坦领土必须证明现有的分配政策符合某些条件，或改变政策以满足一系列标准，包括更广泛的器官地理共享，减少使用等待时间作为分配标准，并建立公平的器官分配系统，使用客观的医疗标准和医疗紧急情况分配供移植的捐赠器官。这一任务导致对所有器官分配政策的审查，并导致OPTN胸器官移植委员会肺分配小组委员会的成立。本文回顾了小组委员会在确定OPTN和移植受者科学登记处的优先事项方面的审议情况，以及一个新的肺分配系统的演变，该系统根据肺分配评分对肺候选人进行排名，并将等待名单和移植后生存概率纳入其中。
This article reviews the development of the new U.S. lung allocation system that took effect in spring 2005. In 1998, the Health Resources and Services Administration of the U.S. Department of Health and Human Services published the Organ Procurement and Transplantation Network (OPTN) Final Rule. Under the rule, which became effective in 2000, the OPTN had to demonstrate that existing allocation policies met certain conditions or change the policies to meet a range of criteria, including broader geographic sharing of organs, reducing the use of waiting time as an allocation criterion and creating equitable organ allocation systems using objective medical criteria and medical urgency to allocate donor organs for transplant. This mandate resulted in reviews of all organ allocation policies, and led to the creation of the Lung Allocation Subcommittee of the OPTN Thoracic Organ Transplantation Committee. This paper reviews the deliberations of the Subcommittee in identifying priorities taken by the OPTN and the Scientific Registry for Transplant Recipients and the evolution of a new lung allocation system that ranks candidates for lungs based on a Lung Allocation Score, incorporating waiting list and posttransplant survival probabilities.