Post-concussion syndrome: Prevalence after mild traumatic brain injury in comparison with a sample without head injury
Post-concussion syndrome: Prevalence after mild traumatic brain injury in comparison with a sample without head injury
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DOI：
10.3109/02699052.2011.635354
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发表时间：
2012-01-01
期刊：
影响因子：
1.9
通讯作者：
Sterr, Annette
中科院分区：
文献类型：
--
作者：
Dean, Philip J. A.;O'Neill, Darragh;Sterr, Annette
主要目标：比较持续性脑震荡后综合征的患病率（PCS;伤后>1年）在轻度创伤性脑损伤（mTBI）和那些没有头部损伤的参与者中的研究设计：119名mTBI参与者和246名没有既往头部损伤的参与者的横断面样本。在线问卷收集了有关脑震荡后症状、认知障碍、焦虑、抑郁、睡眠行为和创伤后应激障碍的数据。通过根据PCS诊断划分以创建四个组来解决样本内的可变性：mTBI + PCS、mTBI-PCS、对照+ PCS和对照-PCS。PCS诊断使用ICD-10标准在所有组中，与控制不需要以前的头部injure.Main结果和结果：PCS是目前在没有头部损伤（34%）的参与者与mTBI（31%）相比，在相似的程度。仅报告了可能由预期偏差引起的头痛，区分了mTBI + PCS组和对照+ PCS组。此外，显着更高的认知问题，观察与mTBI的参与者相比，与control group.Conclusions：持久性PCS，目前定义的，是不是特定的mTBI。这些数据表明，躯体和认知症状最有可能能够区分mTBI后的PCS与一般人群中存在的PCS。为了建立更具体的PCS诊断标准，有必要对这些因素进行进一步的研究。
Primary objective: To compare the prevalence of persistent post-concussion syndrome (PCS; >1 year post-injury) in participants with mild traumatic brain injury (mTBI) and those without head injury.Research design: A cross-sectional sample of 119 participants with mTBI and 246 without previous head injury.Methods: Online questionnaires collected data about post-concussion symptoms, cognitive failures, anxiety, depression, sleep behaviour and post-traumatic stress disorder. Variability within the sample was addressed by splitting by PCS diagnosis to create four groups: mTBI + PCS, mTBI-PCS, Control + PCS and Control-PCS. PCS was diagnosed using ICD-10 criteria in all groups, with controls not requiring previous head injury.Main outcomes and results: PCS was present to a similar extent in participants with no head injury (34%) compared to those with mTBI (31%). Only report of headaches, which could be caused by expectation bias, distinguished between mTBI + PCS and Control + PCS groups. In addition, significantly higher cognitive problems were observed in participants with mTBI compared with the control group.Conclusions: Persistent PCS, as currently defined, is not specific to mTBI. These data suggest that somatic and cognitive symptoms are most likely to be able to distinguish PCS after mTBI from that present in the general population. Further research is necessary into these factors in order to create more specific PCS diagnostic criteria.