Transforming research: engaging patient advocates at all stages of cancer research
Transforming research: engaging patient advocates at all stages of cancer research
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DOI：
10.21037/atm.2018.04.46
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发表时间：
2018-05-01
影响因子：
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通讯作者：
Franco, Aime T.
中科院分区：
文献类型：
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作者：
Ciccarella, AnneMarie;Staley, Alicia C.;Franco, Aime T.
近年来，人们一直在推动将患者和倡导者纳入临床研究，包括临床试验设计和批准过程。此外，倡导者驱动的研究资金增加，导致倡导者在资金审查过程中的席位。然而，尽管取得了一些进展，包括让患者和倡导者参与可能直接或最终影响他们的护理和治疗的临床研究项目，但我们还有很长的路要走，才能使这成为真正包容性的研究参与。我们还有更进一步的工作要做，在整个研究过程中积极纳入患者和倡导者。在这里，我们回顾和目前的计划和项目，已成功地将患者和倡导者纳入转化研究，并提出机制和策略，积极参与整个研究连续体的患者。我们在转化癌症研究中的目标是改善癌症患者的预后。为了更成功和更快地实现这一目标，我们应该在过程的早期将患者驱动的研究问题纳入其中，特别是在基础实验室研究的水平上。
In recent years there has been a push to include patients and advocates in clinical research, including in clinical trial design and approval processes. Additionally, increased advocate-driven research funding has led to seats for advocates in the funding review process. However, despite advances that include having patients and advocates involved in clinical research projects that may directly, or eventually, affect their care and treatment, we have much further to go to make this a truly inclusionary participation in research. We have even further to go to actively incorporate patients and advocates throughout the research continuum. Here we review and present current programs and projects that have successfully incorporated patients and advocates into translational research, and propose mechanism and strategies to actively engage patients throughout the research continuum. Our goal in translational cancer research is to improve outcomes for cancer patients. To more successfully and quickly meet this objective we should incorporate patient driven research questions earlier in the process, specifically at the level of basic benchtop research.