Neutrophil contributions to the induction and regulation of the acute inflammatory response in teleost fish
Neutrophil contributions to the induction and regulation of the acute inflammatory response in teleost fish
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DOI：
10.1189/jlb.3hi0215-064r
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发表时间：
2016-02-01
影响因子：
5.5
通讯作者：
Barreda, Daniel R.
中科院分区：
文献类型：
--
作者：
Havixbeck, Jeffrey J.;Rieger, Aja M.;Barreda, Daniel R.
中性粒细胞对于急性炎症反应是必不可少的，在那里它们充当抵抗浸润病原体的第一道防线。我们报告说，在接收到必要的信号，硬骨鱼（鲫鱼）中性粒细胞离开造血肾，进入循环，并占主导地位的细胞进入炎症部位的初始流入。与哺乳动物不同，硬骨鱼的中性粒细胞代表
Neutrophils are essential to the acute inflammatory response, where they serve as the first line of defense against infiltrating pathogens. We report that, on receiving the necessary signals, teleost (Carassius auratus) neutrophils leave the hematopoietic kidney, enter into the circulation, and dominate the initial influx of cells into a site of inflammation. Unlike mammals, teleost neutrophils represent