Aspergiolide A, a novel anthraquinone derivative with naphtho[1,2,3-de]chromene-2,7-dione skeleton isolated from a marine-derived fungus Aspergillus glaucus
Aspergiolide A, a novel anthraquinone derivative with naphtho[1,2,3-de]chromene-2,7-dione skeleton isolated from a marine-derived fungus Aspergillus glaucus
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Aspergiolide A，一种新型蒽醌衍生物，具有萘并[1,2,3-去]色烯-2,7-二酮骨架，从海洋源性真菌青曲霉中分离出来
DOI：
10.1016/j.tet.2006.11.074
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发表时间：
2007-01-29
期刊：
影响因子：
2.1
通讯作者：
Zhu, Weiming
中科院分区：
文献类型：
--
作者：
Du, Lin;Zhu, Tianjiao;Zhu, Weiming
从海洋真菌灰绿曲霉（Aspergillusglaucus）中分离得到一种具有萘并[1，2，3-de]色烯-2，7-二酮骨架的蒽醌衍生物--蓝绿曲霉A（1）。1的结构和立体化学由NMR和X-射线衍射分析确定。化合物1对A-549、HL-60、BEL-7402和P388细胞系显示出选择性细胞毒性。(c)2006爱思唯尔有限公司保留所有权利。
Aspergiolide A (1), an anthraquinone derivative with naphtho [ 1,2,3 -de] chromene-2,7-di one skeleton, has been isolated from cultures of a marine-derived fungus Aspergillus glaucus. The structure and stereochemistry of 1 was determined by NMR and X-ray diffraction analyses. Compound 1 showed selective cytotoxicities against A-549, HL-60, BEL-7402, and P388 cell lines. (c) 2006 Elsevier Ltd. All rights reserved.