Terahertz pulsed imaging of frozen biological tissues
Terahertz pulsed imaging of frozen biological tissues
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DOI：
10.1063/1.3106616
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发表时间：
2009-03-23
影响因子：
4
通讯作者：
Otani, Chiko
中科院分区：
文献类型：
--
作者：
Hoshina, Hiromichi;Hayashi, Aya;Otani, Chiko
最近，太赫兹波成像已被证明在医学和生物学应用中具有潜力。然而，组织中液态水的吸收阻碍了厚样品的测量。在这项研究中，猪组织被冷冻到低于-33摄氏度的温度，以防止这种吸收。因此，横纹肌和脂肪组织可以清楚地区分在太赫兹时域光谱由于吸收值和折射率的差异。我们展示了吸收率和太赫兹脉冲延迟的二维图，它清楚地显示了组织的空间分布。
Recently, terahertz wave imaging has been shown to have potential in medical and biological applications. However, absorption by liquid water in tissues hinders the measurement of thick samples. In this study, porcine tissue was frozen to temperatures below -33 degrees C to prevent this absorption. Consequently, the striated muscle and adipose tissue could be clearly distinguished in the terahertz time-domain spectra owing to the difference in absorbance values and refractive indices. We demonstrated two-dimensional map of absorbance and terahertz pulse delay, which clearly shows the spatial distribution of the tissues.