The trypanosomatid Rieske iron-sulfur proteins have a cleaved presequence that may direct mitochondrial import.

The trypanosomatid Rieske iron-sulfur proteins have a cleaved presequence that may direct mitochondrial import.
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锥虫 Rieske 铁硫蛋白具有可能指导线粒体输入的切割前序列。

DOI:
10.1016/0167-4889(95)00154-6
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发表时间:
1995
期刊:
Biochimica et biophysica acta
影响因子:
--
通讯作者:
Hajduk,SL
Hajduk,SL
中科院分区:
--
文献类型:
--
作者:
Priest,JW;Hajduk,SL

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我们克隆了编码T.布鲁氏菌细胞色素-C还原酶复合物和C. fasciculata亚基4 cDNA,并已表明亚基4是Rieske铁硫蛋白。锥虫铁硫蛋白的切割前序列类似于传统的线粒体靶向前序列,但小于其他真核生物铁硫蛋白信号肽。
We have cloned the gene that encodes subunit 4 of the T. bruceicytochrome-c reductase complex and a fragment of the C. fasciculata subunit 4 cDNA and have shown that subunit 4 is the Rieske iron-sulfur protein. The cleaved presequences of the trypanosomatid iron-sulfur proteins resemble conventional mitochondrial targeting presequences but are smaller than other eukaryotic iron-sulfur protein signal peptides.