Oxygen consumption and distribution of blood flow in rats climbing a laddermill.
Oxygen consumption and distribution of blood flow in rats climbing a laddermill.
复制标题
爬梯磨的老鼠的耗氧量和血流分布。
DOI：
10.1152/jappl.1990.68.1.241
复制
发表时间：
1990
期刊：
影响因子：
--
通讯作者：
Armstrong,RB
中科院分区：
文献类型：
--
作者：
Norton,KI;Jones,MT;Armstrong,RB
本研究的目的有三：1）确定拒绝在跑步机上跑步的未经训练的大鼠是否会爬上梯子（75度倾斜）; 2）测定未训练大鼠的O2消耗量（VO 2）作为爬梯速度的函数;和3）为了确定未经训练的大鼠对爬梯的循环反应是否与先前报道的在跑步机上跑步的反应相似，相当于VO 2。作为另一项研究的一部分，18只雌性Sprague-Dawley大鼠不会在跑步机上运动，用于测量作为梯式跑步机速度（5-17 m/min）函数的VO 2。从所有18只大鼠获得数据; VO 2作为梯磨机速度的函数线性增加（r = 0.83，y = 3.0 x + 63.2）。24只雌性Sprague-Dawley大鼠也拒绝在跑步机上跑步，用于测量平均动脉压，心率和血流分布（微球）在5和10 m/min的攀登。这些运动强度在代谢上相当于水平跑步机运行在45和60 m/min（VO 2约78和93 ml.min-1.kg-1，分别）。在24只动物中，有23只愿意攀爬。平均动脉压较高（约10%）在爬梯比在等效的跑步机上运行，但心率是相同的。肌肉之间的一般血流量分布作为纤维类型的函数（红色肌肉接受更高的流量）以及肌肉和内脏组织之间的一般血流量分布（肌肉血流量作为运动强度的函数增加，而内脏血流量减少）与大鼠在水平上跑步的数据相似。（250字处删节）
The purpose of this study was threefold: 1) to determine whether untrained rats that refused to run on treadmill would climb on a laddermill (75 degrees incline); 2) to determine O2 consumption (VO2) in untrained rats as a function of laddermill climbing speed; and 3) to determine whether the circulatory response of untrained rats to laddermill climbing is similar to that previously reported for treadmill running at an equivalent VO2. Eighteen female Sprague-Dawley rats that would not perform on a treadmill as part of another study were used to measure VO2 as a function of laddermill speed (5-17 m/min). Data were obtained from all 18 rats; VO2 increased linearly as a function of laddermill speed (r = 0.83, y = 3.0 x + 63.2). Twenty-four female Sprague-Dawley rats that also refused to run on a treadmill were used to measure mean arterial pressure, heart rate, and blood flow distribution (with microspheres) during climbing at 5 and 10 m/min. These exercise intensities were metabolically equivalent to level treadmill running at 45 and 60 m/min (VO2 approximately 78 and 93 ml.min-1.kg-1, respectively). Of the 24 animals, 23 were willing to climb. Mean arterial pressures were higher (approximately 10%) during laddermill climbing than during equivalent treadmill running, but heart rates were the same. General blood flow distribution among muscles as a function of fiber type (with red muscles receiving higher flows) and between muscles and visceral tissues (muscle blood flow increased as a function of exercise intensity while visceral blood flows decreased) were similar to data for rats running on the level.(ABSTRACT TRUNCATED AT 250 WORDS)