REDUCTION OF TRANSMISSION OF SHIGELLOSIS BY CONTROL OF HOUSEFLIES (MUSCA-DOMESTICA)
REDUCTION OF TRANSMISSION OF SHIGELLOSIS BY CONTROL OF HOUSEFLIES (MUSCA-DOMESTICA)
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DOI：
10.1016/0140-6736(91)92657-n
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发表时间：
1991-04-27
期刊：
影响因子：
168.9
通讯作者：
LEVINE, MM
中科院分区：
文献类型：
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作者：
COHEN, D;GREEN, M;LEVINE, MM
在相距数公里的两个军事基地进行的前瞻性交叉干预研究中，评估了控制家蝇对腹泻和志贺氏菌病发病率的影响。1988年初夏，在一个基地采取密集灭蝇措施(主要是诱饵和诱捕策略)，另一个基地作为对照。11周后，随着新队列的到来，第一个基地的干预突然停止，第二个基地在接下来的11周里开始进行干预。第二年夏天，这项研究又重复了一次。总体而言，苍蝇数量比暴露于苍蝇控制措施的基地低%(p=0.024)。与此同时，腹泻疾病的就诊次数下降了42%(p=0.146)，志贺氏菌病的就诊次数下降了85%(p=0.015)，血清转换率下降了76%(p=0.024)，产肠毒素大肠杆菌抗体的就诊次数下降了57%(p=0.006)。研究结果表明，家蝇作为机械媒介传播志贺氏菌(可能还有产肠毒素大肠杆菌)腹泻感染。
The effect of control of houseflies on the incidence of diarrhoea and shigellosis was evaluated in a prospective crossover intervention study at two military field bases several kilometres apart. In early summer, 1988, intensive fly control measures (mainly bait and trap strategy) were introduced on one base, while the other served as a control. After 11 weeks, as new cohorts arrived, the intervention was abruptly discontinued in the first base and instituted in the second for the next 11 weeks. The study was repeated the next summer. Overall, fly counts were 64% lower on the bases exposed to fly control measures (p = 0.024). Concomitantly, clinic visits dropped by 42% (p = 0.146) for diarrhoeal diseases and by 85% for shigellosis (p = 0.015), as did rates of seroconversion, by 76% (p = 0.024) for antibodies to Shigella and by 57% (p = 0.006) for antibodies to enterotoxigenic Escherichia coli. The findings indicate that houseflies, acting as mechanical vectors, transmit Shigella (and possibly enterotoxigenic E coli) diarrhoeal infections.