Repeated genetic adaptation to high altitude in two tropical butterflies
Repeated genetic adaptation to high altitude in two tropical butterflies
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DOI：
10.1101/2021.11.30.470630
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发表时间：
2021-12
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通讯作者：
Gabriela Montejo-Kovacevich;Joana I. Meier;C. Bacquet;I. Warren;Y. F. Chan;M. Kučka;C. Salazar;Nicol Rueda;S. Montgomery;W. McMillan;Krzysztof M. Kozak;Nicola J. Nadeau;Simon H. Martin;C. Jiggins
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作者：
Gabriela Montejo-Kovacevich;Joana I. Meier;C. Bacquet;I. Warren;Y. F. Chan;M. Kučka;C. Salazar;Nicol Rueda;S. Montgomery;W. McMillan;Krzysztof M. Kozak;Nicola J. Nadeau;Simon H. Martin;C. Jiggins
重复的进化可以提供对促进适应新的或变化的环境的机制的洞察。在这里，我们研究适应高海拔在两个分歧的热带蝴蝶，H。erato和H.在安第斯山脉两侧的高海拔地区，它们反复独立地适应。我们对来自海拔样带的518个全基因组进行了测序，发现了高海拔地区的许多选择区域，在多个重复中存在重复的遗传分化，包括异地比较。相比之下，H之间几乎没有“分子平行性”。erato和H.美波美与另外85个全基因组的5个近亲，我们发现，很大比例的分歧地区已经出现了常设的变化和假定的适应性渐渗从高海拔专业物种。总之，我们的研究支持了一个关键作用的常设遗传变异和基因流从预适应物种在促进并行遗传局部适应环境。
Repeated evolution can provide insight into the mechanisms that facilitate adaptation to novel or changing environments. Here we study adaptation to high altitude in two divergent tropical butterflies, H. erato and H. melpomene, which have repeatedly and independently adapted to high elevations on either side of the Andean mountains. We sequenced 518 whole genomes from elevational transects and found many regions under selection at high altitude, with repeated genetic differentiation across multiple replicates, including allopatric comparisons. In contrast, there is little ‘molecular parallelism’ between H. erato and H. melpomene. With a further 85 whole genomes of five close relatives, we find that a large proportion divergent regions have arisen from standing variation and putative adaptive introgression from high-altitude specialist species. Taken together our study supports a key role of standing genetic variation and gene flow from pre-adapted species in promoting parallel genetic local adaptation to the environment.