A DUAL QUATERNION BASED METHOD FOR ESTIMATING MARGINS FOR PLANNING TARGET VOLUMES IN RADIOTHERAPY.
A DUAL QUATERNION BASED METHOD FOR ESTIMATING MARGINS FOR PLANNING TARGET VOLUMES IN RADIOTHERAPY.
复制标题
一种基于双四元数的方法，用于估计放射治疗中规划目标体积的余量。
DOI：
10.1115/detc2020-22569
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发表时间：
2020
期刊：
影响因子：
--
通讯作者：
Langer,Mark
中科院分区：
文献类型：
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作者：
Ge,QJ;Yu,Zihan;Langer,Mark
本文的目的是发展一种基于对偶四元数的头颈部肿瘤放射治疗靶区体积估计方法。辐射靶向的不准确性是造成健康邻近组织偶然暴露的原因，导致显著的发病率和死亡率。本文重点关注治疗过程中肿瘤移位时产生的不准确性。为了解决这个问题，必须扩大临床靶点，以覆盖肿瘤可能移动的区域。由此产生的扩展目标被称为计划目标体积（PTV）。在目前的实践中，位移的旋转分量被忽略，产生规划的目标体积，要么错过了真正的目标运动或大于所需的覆盖目标path.By使用双四元数为基础的运动学formulation，本文表示和捕捉平移和旋转的不准确性。然后，它提出了一个框架，用于计算的PTV扫出的目标，因为它在其范围内的平移和旋转。
This objective of this paper is to develop a dual quaternion based method for estimating target volumes in radiation therapy for head and neck cancer. Inaccuracies in radiation targeting are responsible for incidental exposure of healthy adjacent tissues, causing significant morbidity and mortality. This paper focuses on inaccuracies incurred when a tumor is displaced during treatment. To address this problem, the clinical target must be expanded to cover the region through which the tumor might move. The resulting expanded target is known as the Planning Target Volume (PTV). In the current practice, the rotational components of displacements are neglected, producing planning target volumes that either miss the true target motion or are larger than needed to cover the target path. By using the dual quaternion based kinematic formulation, this paper represents and captures both translational and rotational inaccuracies. It then presents a framework for calculating the PTV swept out by the target as it shifts within its range of translations and rotations.