A guide to the Proteomics Identifications Database proteomics data repository

A guide to the Proteomics Identifications Database proteomics data repository
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DOI:
10.1002/pmic.200900402
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发表时间:
2009-09-01
期刊:
影响因子:
3.4
通讯作者:
Martens, Lennart
Martens, Lennart
中科院分区:
生物学3区
文献类型:
--
作者:
Vizcaino, Juan Antonio;Cote, Richard;Martens, Lennart

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蛋白质组学鉴定数据库(Pride,www.ebi.ac.uk/Pride)是MS来源的蛋白质组学数据的主要储存库之一。在这里,我们指出了Pride作为提交信息库和蛋白质组学数据来源的主要功能。我们描述了通过Pride网络和BioMart界面提供的数据检索和可视化的主要功能。我们还重点介绍了BioMart中的定制查询可以将Pride连接到其他资源(如Reactome、EnSembl或UniProt)以执行极其强大的跨域查询的机制。然后,我们使用新的易于使用、独立于平台的图形用户界面提交工具Pride Converter,展示了在PROM提交过程中的最新改进。最后,我们谈一谈未来的计划以及ProteomExchange财团中的骄傲所扮演的角色。
The Proteomics Identifications Database (PRIDE, www.ebi.ac.uk/pride) is one of the main repositories of MS derived proteomics data. Here, we point out the main functionalities of PRIDE both as a submission repository and as a source for proteomics data. We describe the main features for data retrieval and visualization available through the PRIDE web and BioMart interfaces. We also highlight the mechanism by which tailored queries in the BioMart can join PRIDE to other resources such as Reactome, Ensembl or UniProt to execute extremely powerful across-domain queries. We then present the latest improvements in the PRIDE submission process, using the new easy-to-use, platform-independent graphical user interface submission tool PRIDE Converter. Finally, we speak about future plans and the role of PRIDE in the ProteomExchange consortium.