Seasonal Variation in the Incidence of Aneurysmal Subarachnoid Hemorrhage Associated with Age and Gender: 20-Year Results from the Yamaguchi Cerebral Aneurysm Registry
Seasonal Variation in the Incidence of Aneurysmal Subarachnoid Hemorrhage Associated with Age and Gender: 20-Year Results from the Yamaguchi Cerebral Aneurysm Registry
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DOI：
10.1159/000345247
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发表时间：
2013-01-01
影响因子：
5.7
通讯作者：
Suzuki, Michiyasu
中科院分区：
文献类型：
--
作者：
Ishihara, Hideyuki;Kunitsugu, Ichiro;Suzuki, Michiyasu
背景：本研究是一项在几乎没有气候差异的地区进行的脑动脉瘤登记研究。根据20多年来收集的资料，分析了动脉瘤破裂所致蛛网膜下腔出血（SAH）的季节变化和特点。方法：本研究纳入了1986年至2005年山口县的5,007例蛛网膜下腔出血患者。按月、性别、年龄、严重程度和动脉瘤部位分析发病率。结果：在妇女中，观察到季节性变化，特别是在年龄≥ 50岁的妇女中。在50-69岁人群中，10月发病率最高，6月发病率最低（峰谷比= 1.72）。在年龄>= 70岁时，情况略有不同，12月发病率最高，7月发病率最低（峰谷比= 1.48）。然而，男性总体无季节性变化;仅限于年龄≥ 70岁的老年男性，1月发病率最高，7月最低（峰谷比= 2.9）。动脉瘤的部位和严重程度与季节变化无关。结论：本研究显示SAH的发病具有季节性变化。SAH的季节变化因年龄和性别而异。版权所有（C）2013 S. Karger AG，巴塞尔
Background: This study was a cerebral aneurysm registry study conducted in a region with few climatic differences. Based on data collected for over 20 years, seasonal variations and characteristics of subarachnoid hemorrhage (SAH) due to ruptured aneurysms were analyzed. Methods: This study included 5,007 patients in the Yamaguchi Prefecture with aneurysmal SAH between 1986 and 2005. Incidence rates by month, sex, age, severity, and aneurysm site were analyzed. Results: In women, seasonal variation was observed, in particular among those aged >= 50 years. Among those aged 50-69 years, the highest incidence was in October, and the nadir was in June (peak-to-trough ratio = 1.72). At age >= 70 years, this was slightly different, with the highest incidence in December and the nadir in July (peak-to-trough ratio = 1.48). However, there was no seasonal variation in men overall; it was limited to elderly men at age >= 70 years, with the highest incidence in January and the nadir in July (peak-to-trough ratio = 2.9). Aneurysm site and severity showed no relationship with seasonal variation. Conclusion: The present study shows seasonal variations in the onset of SAH. Seasonal variations in SAH differed depending on age and sex. Copyright (C) 2013 S. Karger AG, Basel