CONTROL OF RETINAL AND CHOROIDAL BLOOD-FLOW
CONTROL OF RETINAL AND CHOROIDAL BLOOD-FLOW
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DOI：
10.1038/eye.1990.43
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发表时间：
1990-01-01
期刊：
影响因子：
3.9
通讯作者：
SPERBER, GO
中科院分区：
文献类型：
--
作者：
BILL, A;SPERBER, GO
早期的研究控制视网膜和脉络膜血流的审查和一些最近的观察光对视网膜代谢和视网膜和脉络膜血流的猴子（Macaca fascicularis）的初步形式报告。视网膜由视网膜血管和脉络膜血管滋养，在视网膜血管中血流是自动调节的，在脉络膜血管中没有自动调节。使用Sokoloff的脱氧葡萄糖方法的研究表明，闪烁的光倾向于增加内层视网膜的代谢，而恒定的光减少外层视网膜的代谢。视网膜血流在闪烁的光，8赫兹，高于在恒定的光。脉络膜的交感神经可能参与了一种保护机制，防止在战斗和逃跑的情况下过度灌注，血压急剧升高。面神经含有副交感血管扩张纤维脉络膜;这些纤维的生理意义是未知的。神经肽NPY、VIP和PHI可能参与眼内的自主反射。
Earlier studies on the control of retinal and choroidal blood flow are reviewed and some recent observations on the effects of light on retinal metabolism and retinal and choroidal blood flow in monkeys (Macaca fascicularis) are reported in preliminary form. The retina is nourished by the retinal blood vessels, where blood flow is autoregulated and the choroidal blood vessels where autoregulation is absent. Studies with the deoxyglucose method of Sokoloff indicate that flickering light tends to increase the metabolism of the inner retina, while constant light reduces the metabolism in the outer retina. Retinal blood flow in flickering light, 8 Hz, is higher than in constant light. The symathetic nerves of the choroid are probably involved in a protective mechanism, preventing overperfusion in fight and flight situations with acute increments in blood pressure. The facial nerve contains parasympathetic vasodilator fibres to the choroid; the physiological significance of these fibres is unknown. The neuropeptides NPY, VIP and PHI are likely to be involved in autonomic reflexes in the eye.