Prevalence study of primary dystonia in Iceland
Prevalence study of primary dystonia in Iceland
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DOI：
10.1002/mds.20674
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发表时间：
2006-03-01
影响因子：
8.6
通讯作者：
Sveinbjornsdottir, S
中科院分区：
文献类型：
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作者：
Asgeirsson, H;Jakobsson, F;Sveinbjornsdottir, S
在冰岛，所有类型的原发性肌张力障碍的粗患病率为37.1/10(5)(可信区间为30.4-44.9)。局灶性肌张力障碍患病率最高(31.2/10(5))，其次为节段性肌张力障碍(3.1/10(5))、多灶性肌张力障碍(2.4/10(5))和全身性肌张力障碍(0.3/10(5))。颈部肌张力障碍最常见(11.5/10(5))，其次为肢体肌张力障碍(8.0/10(5))、喉肌张力障碍(5.9/10(5))、眼睑痉挛(3.1/10(5))、口下颌肌张力障碍(2.8/10(5))。男女之比为1：1.9(P=0.0007)，除下颌肌张力障碍外，其余亚型均为女性多于男性。所有患者的平均发病年龄为42.7岁(3-82岁)。这种原发性肌张力障碍的患病率高于大多数报道的研究，可能是因为更全面的查明，但肌张力障碍亚型的相对频率相似。(C)2005年运动无序协会。
In Iceland, the crude prevalence for all types of primary dystonia was 37.1/10(5) (confidence interval, 30.4-44.9). Focal dystonia had the highest prevalence (31.2/10(5)), followed by segmental (3.1/10(5)), multifocal (2.4/10(5)) and generalized dystonia (0.3/10(5)). Cervical dystonia was the most common focal dystonia (11.5/10(5)), followed by limb dystonia (8.0/10(5)), laryngeal dystonia (5.9/10(5)), blepharospasm (3.1/10(5)), and oromandibular dystonia (2.8/10(5)). The male:female ratio for all patients was 1:1.9 (P = 0.0007), and females Outnumbered males in all subtypes except Oromandibular dystonia. Mean age of onset for all patients was 42.7 years (range, 3-82 years). This prevalence of primary dystonia is higher than in most reported studies, possibly because of more complete ascertainment but the relative frequencies of dystonia subtypes is similar. (c) 2005 Movement Disorder Society.