PLASTICITY OF MOTOR BEHAVIOR IN MONKEYS WITH CROSSED FORELIMB NERVES
PLASTICITY OF MOTOR BEHAVIOR IN MONKEYS WITH CROSSED FORELIMB NERVES
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DOI：
10.1126/science.6836289
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发表时间：
1983-01-01
期刊：
影响因子：
56.9
通讯作者：
NORMAN, J
中科院分区：
文献类型：
--
作者：
BRINKMAN, C;PORTER, R;NORMAN, J
通过手术将支配前臂和手部屈肌的神经(尺神经或正中神经)与支配伸肌的神经(桡神经)交叉连接，反之亦然，在再生后，猴子表现出良好的(尺骨-放射状交叉)到中等(正中-放射状交叉)的运动控制能力。偶尔也会看到对抗性运动反应，但这些反应几乎立即得到纠正。对交叉神经的刺激表明，它们已支配了拮抗肌群。这些结果揭示了灵长类中枢神经系统适应周围神经变化对运动执行施加的粗暴干扰的能力。
Monkeys in which nerves innervating the flexor muscles of the forearm and hand (the ulnar or the median nerve) were surgically cross-united with the nerve innervating the extensor muscles (the radial nerve), and vice versa, showed excellent (ulnar-radial crosses) to moderate (median-radial crosses) control of movement performance after regeneration. Antagonistic movement responses were seen occasionally, but these were corrected almost immediately. Stimulation of the crossed nerves showed that they had innervated the antagonistic muscle groups. The results reveal the capacity of the primate central nervous system to adapt to gross disturbances imposed on the execution of movements by changes in peripheral innervation.