Black hemostatic sponge based on facile prepared cross-linked graphene.
Black hemostatic sponge based on facile prepared cross-linked graphene.
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DOI：
10.1016/j.colsurfb.2015.04.067
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发表时间：
2015-08
期刊：
影响因子：
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通讯作者：
Kecheng Quan;Guofeng Li;Di Luan;Qipeng Yuan;Lei Tao;Xing Wang
中科院分区：
文献类型：
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作者：
Kecheng Quan;Guofeng Li;Di Luan;Qipeng Yuan;Lei Tao;Xing Wang
在这项研究中，我们首次证明了交联石墨烯海绵（CGS）作为一种极好的止血剂的显着止血性能。CGS可以立即（<40 ms）吸收血浆，形成血细胞层，并促进随后的凝血。CGS与血细胞界面的相互作用表明，血细胞和血小板在创面上的富集是血液快速凝固的主要原因。动物体外动态全血凝血试验进一步凸显了CGS的有效性。由于这种便携式黑色海绵制备简单、成本低、无毒、保存期长，因此在创伤治疗中具有很大的应用潜力。
In this study, we demonstrate for the first time the remarkable hemostatic performance of a cross-linked graphene sponge (CGS) as a superb hemostat. The CGS can absorb plasma immediately (<40 ms) to form a blood cell layer and promotes subsequent clotting. The interaction between the interface of the CGS and blood cells reveals that the fast blood coagulation is primarily attributed to the enrichment of hemocytes and platelets on the wound surface. Anin vitrodynamic whole-blood clotting test further highlights the effectiveness of the CGS. Considering the facile preparation, low cost, nontoxicity, and long shelf life of the portable black sponge, the CGS has great potential for trauma treatment.