Prevalence of dyslipidemia and associated risk factors in Turkish adults
Prevalence of dyslipidemia and associated risk factors in Turkish adults
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DOI：
10.1016/j.jacl.2013.12.011
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发表时间：
2014-04-01
影响因子：
4.4
通讯作者：
Gedik, Vedia
中科院分区：
文献类型：
--
作者：
Bayram, Fahri;Kocer, Derya;Gedik, Vedia
背景和目的：血脂异常是冠心病的主要危险因素。这项研究的目的是确定土耳其成年人中血脂异常的患病率及其与其他心血管危险因素的关系。方法：这项研究包括来自土耳其7个省的4309名20岁至83岁的人。采用分层抽样的方法抽取市中心、区、村的调查对象。测量了体重、身高、腰围和臀围。采血测定血糖、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)和甘油三酯(TG)，并用自动分析仪测定这些参数。结果：4309例受试者中，43%为高TC者，41.5%为低HDLc者，36.2%为高LDLc者，35.7%为高TG者。在这些测量中，78.7%的男性和80.4%的女性至少诊断出一种血脂异常。高TC、LDL-C、TO的患病率随年龄增长而升高，46~65岁年龄组患病率最高。总胆固醇、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇和高密度脂蛋白胆固醇的平均值(mg/dL)分别为194.2+/-47.7、117.7+/-41.1、50.3+/-16.3和145.4+/-96.3。血脂异常与年龄、体重指数、腰围、空腹血糖、血压呈正相关，与海拔高度负相关。结论：土耳其血脂异常的高发是一个重要的公共卫生问题。应加强公共卫生预防措施，以便更好地诊断和综合治疗土耳其的血脂异常。(C)2014年全国油脂协会。版权所有。
BACKGROUND AND OBJECTIVES: Dyslipidemia is a modifiable major risk factor for coronary heart disease. The objective of this study was to determine the prevalence of dyslipidemia among Turkish adults and its associations with other cardiovascular risk factors.METHODS: This study included 4309 people ages 20 to 83 years old from 7 provinces of Turkey. People from the city centers, districts, and villages were selected by a stratified sampling method. Weight, height, and waist and hip circumferences were measured. Blood samples were obtained to determine glucose, total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglycerides (TG); these parameters were measured with an auto-analyzer. Dyslipidemia was defined according to National Cholesterol Education Program Adult Treatment Panel III diagnostic criteria.RESULTS: Of 4309 subjects, 43% had high TC, 41.5% had low HDL-C, 36.2% had high LDL-C, and 35.7% had high TG. Of these measures, at least 1 lipid abnormality was diagnosed in 78.7% of men and 80.4% of women. The prevalence of high TC, LDL-C, and TO increased with age, with the highest prevalence in the 46-to-65-year-old age group. The mean values (mg/dL) of TC, LDL-C, HDL-C, and TO were 194.2 +/- 47.7, 117.7 +/- 41.1, 50.3 +/- 16.3, and 145.4 +/- 96.3, respectively. Dyslipidemia was positively associated with age, body mass index, waist circumference, fasting blood glucose, and blood pressure, and negatively associated with altitude.CONCLUSIONS: The high prevalence of dyslipidemia in Turkey is an important public health problem. Enhanced public health preventive measures should be implemented to better diagnose and comprehensively treat dyslipidemia in Turkey. (C) 2014 National Lipid Association. All rights reserved.