Associations of Insulin Resistance and Glycemic Control with the Risk of Kidney Stones
Associations of Insulin Resistance and Glycemic Control with the Risk of Kidney Stones
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DOI：
10.2169/internalmedicine.51.6426
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发表时间：
2012-01-01
影响因子：
1.2
通讯作者：
Atsumi, Yoshihito
中科院分区：
文献类型：
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作者：
Kabeya, Yusuke;Kato, Kiyoe;Atsumi, Yoshihito
目的探讨胰岛素抵抗和血糖控制与肾结石发病风险的关系。方法对日本东京斋世凯中心医院就诊的2171名健康日本人进行横断面研究。根据空腹血清胰岛素、胰岛素抵抗稳态模型评估(HOMA-IR)、空腹血糖(FPG)和糖化血红蛋白(HbA1c)四项指标计算患肾结石的优势比(OR)，调整肾结石的可能危险因素。结果空腹血清胰岛素和HOMA-IR与肾结石风险无显著相关，而空腹血糖和HbA1c显著相关。与空腹血糖为
Objective The associations of insulin resistance and glycemic control with the risk of kidney stones were explored.Methods Generally healthy Japanese (n=2,171) who visited Saiseikai Central Hospital (Tokyo, Japan) for a health check were included in a cross-sectional study. We calculated odds ratios (OR) of having kidney stones in terms of four measures: fasting serum insulin, homeostasis model assessment of insulin resistance (HOMA-IR), fasting plasma glucose (FPG) and glycosylated hemoglobin (HbA1c), adjusting for possible risk factors for kidney stones.Results Fasting serum insulin and HOMA-IR were non-significantly associated with the risk of kidney stones, whereas FPG and HbA1c were significantly associated. Compared with those with an FPG of