Area MT Encodes Three-Dimensional Motion
Area MT Encodes Three-Dimensional Motion
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DOI：
10.1523/jneurosci.1081-14.2014
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发表时间：
2014-11-19
影响因子：
5.3
通讯作者：
Kohn, Adam
中科院分区：
文献类型：
--
作者：
Czuba, Thaddeus B.;Huk, Alexander C.;Kohn, Adam
我们使用视觉信息来确定我们与三维（3D）世界中其他物体的动态关系。尽管对视觉运动处理的研究已经进行了几十年，但人们仍然不清楚3D方向——包括朝向或远离观察者的运动轨迹——是如何在视觉皮层中表现和处理的。区域MT与视觉运动和深度的处理密切相关，但之前的工作几乎没有发现3D方向敏感性本身的证据。本研究使用丰富的双目运动刺激集合来揭示麻醉猕猴MT区的大多数神经元编码3D运动信息。这种对3D运动的调整源于多种机制，包括两只眼睛的不同运动偏好，以及两只眼睛受到刺激时这些信号的非线性相互作用。使用一种新的方法功能性双目对准，我们能够排除静态视差调整对我们观察到的3D运动调整的贡献。我们提出MT的一个主要功能是对三维运动进行编码，这对于判断动态现实环境中物体的运动至关重要。
We use visual information to determine our dynamic relationship with other objects in a three-dimensional (3D) world. Despite decades of work on visual motion processing, it remains unclear how 3D directions-trajectories that include motion toward or away from the observer-are represented and processed in visual cortex. Area MT is heavily implicated in processing visual motion and depth, yet previous work has found little evidence for 3D direction sensitivity per se. Here we use a rich ensemble of binocular motion stimuli to reveal that most neurons in area MT of the anesthetized macaque encode 3D motion information. This tuning for 3D motion arises from multiple mechanisms, including different motion preferences in the two eyes and a nonlinear interaction of these signals when both eyes are stimulated. Using a novel method for functional binocular alignment, we were able to rule out contributions of static disparity tuning to the 3D motion tuning we observed. We propose that a primary function of MT is to encode 3D motion, critical for judging the movement of objects in dynamic real-world environments.