CHROMAFFIN CELLS, MAST CELLS AND MELANIN .1. GRANULAR CELLS OF SKIN
CHROMAFFIN CELLS, MAST CELLS AND MELANIN .1. GRANULAR CELLS OF SKIN
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DOI：
10.1677/joe.0.0220059
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发表时间：
1961-01-01
影响因子：
4
通讯作者：
HEATH, ID
中科院分区：
文献类型：
--
作者：
COUPLAND, RE;HEATH, ID
对手术或活检获得的3-70岁的男性和女性的皮肤标本进行了检查。标本取自腹部、肩部、乳房、腰部、小腿和足部。材料用多种方法固定，包括缓冲的福尔马林-重铬酸盐(pH=6)。制备切片，用多种方法进行染色。我们鉴定了三种类型的人肥大细胞。黑色素定位于表皮细胞和真皮细胞。一些肥大细胞和真皮黑素载体是多态的，具有减弱的分支过程。这些细胞对Giemsa染色有亲和力。比较肾上腺髓质和腹主动脉旁嗜铬细胞与皮肤颗粒细胞的染色反应。未发现含有升压胺的真皮嗜铬细胞。
Pieces of human skin obtained at operation or by biopsy from subjects of both sexes aged 3-70 years were examined. Specimens were taken from abdomen, shoulder, breast, loin, calf and foot. Material was fixed by a variety of methods including buffered formol-dichromate (pH6). The sections were prepared and stained by a variety of methods. Three types of human mast cells were identified. Melanin was localized in both epidermal and dermal cells. Some mast cells and dermal melanophores are polymorphic and possess attenuated branching processes. These cells have an affinity for Giemsa stain. The staining reactions of adrenal medullary and para-aortic chromaffin cells were compared with those of the granular cells of skin. No evidence of pressor amine-containing dermal chromaffin cells was found.