Fatal human poisoning with PadanTM: a cartap-containing pesticide

Fatal human poisoning with PadanTM: a cartap-containing pesticide
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DOI:
10.3109/15563650903505166
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发表时间:
2010-02
影响因子:
3.3
通讯作者:
E. Kurisaki;Naho Kato;T. Ishida;A. Matsumoto;K. Shinohara;K. Hiraiwa
E. Kurisaki;Naho Kato;T. Ishida;A. Matsumoto;K. Shinohara;K. Hiraiwa
中科院分区:
医学3区
文献类型:
--
作者:
E. Kurisaki;Naho Kato;T. Ishida;A. Matsumoto;K. Shinohara;K. Hiraiwa

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我们报告了一名摄入约13 g Padan SG™(一种含有杀螟丹的杀虫剂)的患者。摄入后,患者出现多次癫痫发作和呼吸困难,并失去意识。尽管在中毒的早期阶段进行了治疗,但患者没有康复,并于住院的第五天死亡。死亡原因是多系统器官衰竭。毒理学分析结果如下:沙蚕毒素(杀螟丹代谢物)在血浆、尿液和胃液中的浓度分别为10.6微克/毫升、18.2微克/毫升和2.6毫克/毫升。通过Triage® DOA Panels和使用有机磷酸盐检测试剂盒对尿液进行药物筛查的结果为阴性。
We report a patient who ingested about 13 g of Padan SG™, a cartap-containing pesticide. After ingestion, the patient developed multiple seizures and dyspnea and lost consciousness. The patient did not recover and died on the fifth hospital day despite treatment at the early stage of poisoning. The cause of death was multisystem organ failure. Results of toxicological analysis were as follows: concentrations of nereistoxin (cartap metabolite) were 10.6 μg/mL in plasma, 18.2 μg/mL in urine, and 2.6 mg/mL in gastric fluid. Results of drug screening of urine by Triage® DOA Panels and using an organophosphate detection kit were negative.