High-resolution CT findings of lung disease in patients with polymyositis and dermatomyositis
High-resolution CT findings of lung disease in patients with polymyositis and dermatomyositis
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DOI：
10.1097/00005382-199623000-00002
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发表时间：
1996-09-01
影响因子：
3.3
通讯作者：
Nakamura, H
中科院分区：
文献类型：
--
作者：
Ikezoe, J;Johkoh, T;Nakamura, H
本研究的目的是利用高分辨率计算机断层扫描（HRCT）确定多发性肌炎和皮肌炎患者间质性肺病的类型和分布。回顾性分析25例多发性肌炎/皮肌炎患者的高分辨率CT表现及分布。在14例患者中，病理诊断为肺部疾病。同时对三个肺标本进行了研究。结果23例患者HRCT异常表现如下：磨玻璃影（92%）、线状影（92%）、不规则界面（88%）、空域实变（52%）、实质微结节（28%）、蜂窝状（16%）。空域固结率相对较高（52%），蜂窝率较低（16%）。2例广泛实变的患者证实有弥漫性肺泡损伤；8例胸膜下带状混浊（n = 5）和/或空域实变（n = 7）有闭塞性细支气管炎组织性肺炎，4例蜂窝患者有常见的间质性肺炎。我们得出结论，多肌炎/皮肌炎患者的HRCT表现是非特异性的，然而，观察到空域实变的高发率和蜂窝状的低发率。主要的HRCT模式提示多发性肌炎/皮肌炎的病理过程。
The purpose of this study was to determine the type and distribution of interstitial lung disease seen in patients with polymyositis and dermatomyositis, using high-resolution computed tomography (HRCT). The presence and distribution of high resolution CT findings were retrospectively evaluated in 25 patients with polymyositis/dermatomyositis. In 14 patients, a pathological diagnosis of pulmonary disease was obtained. Three lung specimens were also studied. Results showed that 23 patients had abnormal HRCT showing the following abnormalities: ground glass opacities (92%), linear opacities (92%), irregular interfaces (88%), airspace consolidation (52%), parenchymal micronodules (28%), and honeycombing (16%). A relatively high prevalence of airspace consolidation (52%) and a low prevalence of honeycombing (16%) were observed. Two patients with extensive consolidation proved to have diffuse alveolar damage; eight patients with either subpleural band-like opacities (n = 5) and/or airspace consolidation (n = 7) had bronchiolitis obliterans organizing pneumonia four patients with honeycombing had usual Interstitial pneumonitis. We conclude chat HRCT findings in patients with polymyositis/dermatomyositis are nonspecific However, a high prevalence of airspace consolidation and a low prevalence of honeycombing were observed. Predominant HRCT patterns are suggestive of the pathologic processes occurring in polymyositis/dermatomyositis.