ENDOGENOUS ENDOPHTHALMITIS AMONG PATIENTS WITH CANDIDEMIA
ENDOGENOUS ENDOPHTHALMITIS AMONG PATIENTS WITH CANDIDEMIA
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DOI：
10.1016/s0161-6420(82)34722-3
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发表时间：
1982-01-01
期刊：
影响因子：
13.7
通讯作者：
GENTRY, LO
中科院分区：
文献类型：
--
作者：
PARKE, DW;JONES, DB;GENTRY, LO
前瞻性检查了 38 名真菌血症患者是否发生眼内炎。 27 名白色念珠菌菌血症患者中，有 10 名（37%）出现眼内炎。只有一名非白色念珠菌真菌血症患者出现眼内炎。在研究的预选因素中，只有血液透析和肠外营养过剩与眼内炎发病率增加相关。乳胶凝集测定的抗体滴度对眼内炎的预测价值不大。 Antigen titers by latex agglutination were performed in four cases with endophthalmitis.四名患者中的三名均显示出抗原血症，所有患者的抗体血清学均为阴性。尽管尚无定论，但初步数据表明该测试可能具有临床价值。在评估真菌血症患者时，应考虑定期进行检眼镜检查。
Thirty-eight patients with fungemia were examined prospectively for development of endophthalmitis. Endophthalmitis was present in 10 of 27 (37%) patients withCandida albicansfungemia. Only one patient with nonalbicans fungemia developed endophthalmitis. Of the preselected factors studied, only hemodialysis and parenteral hyperalimentation correlated with an increased incidence of endophthalmitis. Antibody titers by latex agglutination were of little predictive value for endophthalmitis. Antigen titers by latex agglutination were performed in four cases with endophthalmitis. Antigenemia was demonstrated in three of the four patients, all of whom had negative antibody serologies. Although inconclusive, the preliminary data indicate the test may prove to be of clinical value. Periodic ophthalmoscopic examinations should be considered mandatory in the evaluation of patients with fungemia.