Cervical cytological study in unhealthy and healthy looking cervix

Cervical cytological study in unhealthy and healthy looking cervix
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不健康和健康宫颈的宫颈细胞学研究

DOI:
10.3126/njog.v2i2.1454
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发表时间:
2008
影响因子:
--
通讯作者:
A. Rana
A. Rana
中科院分区:
--
文献类型:
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作者:
N. Pradhan;K. Giri;A. Rana

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目的:比较具有健康/不健康子宫颈的女性的子宫颈细胞学检查。方法:对在加德满都妇产科教学医院妇科门诊就诊的 200 名女性(其中 100 名子宫颈健康,100 名子宫颈不健康)进行了一项关于子宫颈抹片检查的前瞻性研究。比较两组的细胞学报告。结果:8 名宫颈不健康的女性出现宫颈发育不良,其中 7 名是轻度发育不良,1 名是重度发育不良。在子宫颈健康的女性中,5 名患有轻度发育不良,1 名患有中度发育不良。 82% 宫颈健康的女性和 83% 宫颈不健康的女性患有非特异性炎症。 Women who were married before 20 years (p=0.04) and had higher parity (3.3 Vs 2.8) were more likely to have unhealthy cervix (p=0.03).阴道分泌物过多在子宫颈不健康的女性中很常见 (p=0.0009)。结论:与健康宫颈相比,宫颈不健康的女性的发育不良程度略高,但差异无统计学意义。因此,这项研究强调了对健康和不健康的子宫颈进行普遍筛查的重要性。关键词:宫颈癌、目视筛查、子宫颈抹片检查、宫颈细胞学检查、宫颈发育不良
Aim:  To compare cervical cytology in women with healthy/unhealthy cervix. Methods:  A prospective study on Pap smear was performed including 200 women, 100 with healthy and 100 with unhealthy cervix, attending outpatient Gynaecology clinic of the Department of Ob/Gyn TU Teaching Hospital, Kathmandu. The cytology report was compared in the two groups. Results:  Cervical dysplasia was seen in 8 women with unhealthy cervix, 7 were mild and one was severe dysplasia. In the women with healthy cervix, 5 had mild and one had moderate dysplasia. Eighty two percent of women with healthy cervix and 83% of women with unhealthy cervix had non-specific inflammation. Women who were married before 20 years (p=0.04) and had higher parity (3.3 Vs 2.8) were more likely to have unhealthy cervix (p=0.03). Excessive vaginal discharge was common in women with unhealthy cervix (p=0.0009). Conclusion:  Dysplasia was slightly higher among the women with unhealthy cervix in comparision to healthy cervix but the difference was not statistically significant. Hence this study emphasizes on the importance of universal screening of both the healthy and unhealthy looking cervix. Key Words:  carcinoma cervix, visual screening, Pap smear, cervical cytology, cervical dysplasia