Prestroke physical activity and early functional status after stroke
Prestroke physical activity and early functional status after stroke
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DOI：
10.1136/jnnp.2008.170027
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发表时间：
2009-09-01
影响因子：
11
通讯作者：
Meschia, J. F.
中科院分区：
文献类型：
--
作者：
Stroud, N.;Mazwi, T. M. L.;Meschia, J. F.
背景资料：身体活动作为中风和心血管疾病的可改变的危险因素的重要性是有据可查的。运动对卒中严重程度和卒中结局的影响尚不清楚。本研究旨在评估该effect.Methods：缺血性卒中遗传学研究中招募的患者收集的数据进行了审查，中风前自我报告的活动水平和四项措施的中风结果评估在登记和大约3个月后登记。Logistic回归被用来评估体力活动和中风的结果之间的关联，未调整和调整患者的characteristics.Results：共673例患者入组; 50.5%的报告有氧体力活动少于每周一次，28.5%的报告有氧体力活动每周一到三次，21%的报告有氧体力活动每周四次或更多。中度和高度体力活动的患者在入组时更有可能具有较高的Barthel指数（BI）评分。运动和牛津残疾量表（OHS）的良好结果也有类似的联系。3个月随访后，中度活动仍然与高BI评分相关。没有显着的关联检测活动和OHS或格拉斯哥结果量表在后续调整后的患者feature.Conclusions：中风前的身体活动水平较高的自我报告可能与中风后的功能优势。我们的研究结果应该被视为探索性的，需要确认，最好是在一个老年人群的运动纵向研究。
Background: The importance of physical activity as a modifiable risk factor for stroke in particular and cardiovascular disease in general is well documented. The effect of exercise on stroke severity and stroke outcomes is less clear. This study aimed to assess that effect.Methods: Data collected for patients enrolled in the Ischemic Stroke Genetics Study were reviewed for prestroke self-reported levels of activity and four measures of stroke outcome assessed at enrolment and approximately 3 months after enrolment. Logistic regression was used to assess the association between physical activity and stroke outcomes, unadjusted and adjusted for patient characteristics.Results: A total of 673 patients were enrolled; 50.5% reported aerobic physical activity less than once a week, 28.5% reported aerobic physical activity one to three times weekly, and 21% reported aerobic physical activity four times a week or more. Patients with moderate and high levels of physical activity were more likely to have higher Barthel Index (BI) scores at enrolment. A similar association was detected for exercise and good outcomes for the Oxford Handicap Scale (OHS). After 3 months of follow-up, moderate activity was still associated with a high BI score. No significant association was detected for activity and the OHS or Glasgow Outcome Scale at follow-up after adjustment for patient characteristics.Conclusions: Higher levels of self-reported prestroke physical activity may be associated with functional advantages after stroke. Our findings should be seen as exploratory, requiring confirmation, ideally in a longitudinal study of exercise in an older population.