Pulmonary hypertension in chronic neonatal lung disease
Pulmonary hypertension in chronic neonatal lung disease
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DOI：
10.1016/j.prrv.2010.05.001
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发表时间：
2010-09-01
影响因子：
5.8
通讯作者：
Fitzgerald, Dominic A.
中科院分区：
文献类型：
--
作者：
Farquhar, Michael;Fitzgerald, Dominic A.
肺动脉高压是慢性新生儿肺病 [CNLD] 的一种罕见但极具挑战性的并发症，因为它发生在“新支气管肺发育不良 [BPD]”中。肺动脉高压的存在可能是亚临床的，并且经常被忽视，因为除了更严重的 CNLD 儿童病例外，其他所有病例都没有考虑到肺动脉高压。虽然治疗的主要方法是补充氧气和时间，并且大多数儿童的肺动脉高压会随着肺的生长而得到缓解，但新的药物治疗的出现为更严重的肺动脉高压病例提供了稳定性，或许还有更好的预后。 (C) 2010 Elsevier Ltd. 保留所有权利。
Pulmonary hypertension is an uncommon but significantly challenging complication of chronic neonatal lung disease [CNLD] as it occurs in the "new bronchopulmonary dysplasia [BPD]". The presence of pulmonary hypertension may be sub-clinical and is often overlooked as it is not considered in all but the more severe cases of children with CNLD. Whilst the mainstays of therapy are supplemental oxygen and time and the majority of children will have resolution of their pulmonary hypertension with lung growth, the advent of newer pharmacological treatments has offered stability and perhaps a better prognosis for more severe cases of pulmonary hypertension. (C) 2010 Elsevier Ltd. All rights reserved.