The effects of immunization against luteinizing hormone-releasing hormone on performance, sexual development, and levels of boar taint-related compounds in intact male pigs.
The effects of immunization against luteinizing hormone-releasing hormone on performance, sexual development, and levels of boar taint-related compounds in intact male pigs.
复制标题
黄体生成素释放激素免疫对未绝育公猪的生产性能、性发育以及公猪异味相关化合物水平的影响。
DOI：
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发表时间：
1994
影响因子：
3.3
通讯作者：
E. Squires
中科院分区：
文献类型：
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作者：
Michel Bonneau;R. Dufour;C. Chouvet;C. Roulet;W. Meadus;E. Squires
研究了新开发的抗LH-RH疫苗对幼龄完整雄性猪的生产性能、性发育和公猪异味相关化合物发生率的影响。在29 kg BW时，将40只杂交完整雄性和20只去势动物分配至3组。去势和一半的完整雄性动物未接受治疗。剩余的完整雄性动物在29 kg和89 kg BW时再次进行抗LH-RH免疫接种。所有猪在105 kg BW时屠宰。与对照组相比，去势组的饲料利用率降低了10%，肌肉含量降低了5%，胴体脂肪含量增加了26%。免疫组和对照组完整雄性之间的生长性能和胴体性状无显著差异。屠宰时测量的生殖道重量通过免疫降低（P <或= .002）。在89 kg BW时血浆睾酮浓度没有受到显著影响，而在105 kg BW时，免疫组的血浆睾酮浓度比对照组的完整雄性低7倍（P <0.001）。在屠宰时测量的脂肪雄酮水平从对照组的0.66 +/-0.07微克/克显著降低（P <0.001）到免疫完整雄性的0.21 +/-0.01微克/克。睾丸类固醇的生物合成率，在体外测定，免疫去势降低。脂肪粪臭素水平非常低，三组之间没有显着差异。目前的结果表明，抗LHRH免疫是有效的，在降低雄烯酮，公猪污点相关的化合物的水平，虽然有一个有限的影响，对动物的性能。
The effect of a newly developed anti-LH-RH vaccine on the performance, sexual development, and incidence of boar taint-related compounds was investigated in young intact male pigs. At 29 kg BW, 40 crossbred intact males and 20 castrates were allocated to three groups. Castrates and half of the intact males were untreated. The remaining intact males were immunized against LH-RH at 29 kg and again at 89 kg BW. All pigs were slaughtered at 105 kg BW. Compared with control intact males, feed efficiency in castrates was decreased by 10%, muscle content was reduced by 5%, and carcass fat content was increased by 26%. Growth performance and carcass traits did not differ significantly between immunized and control intact males. Genital tract weight, measured at slaughter, was decreased (P < or = .002) by immunization. Plasma testosterone concentrations were not significantly affected at 89 kg BW, whereas they were sevenfold lower (P < .001) in immunized than in control intact males at 105 kg BW. Fat androsterone levels, measured at slaughter, were substantially reduced (P < .001) from .66 +/- .07 microgram/g in control to .21 +/- .01 microgram/g in immunized intact males. Rates of testicular steroid biosynthesis, measured in vitro, were decreased by immunocastration. Fat skatole levels were very low and did not differ significantly between the three groups. The present results demonstrate that anti-LHRH immunization was effective in reducing the level of androstenone, a boar taint-related compound, although having a limited effect on the performance of the animals.