Dengue: a continuing challenge for molecular biology.
Dengue: a continuing challenge for molecular biology.
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DOI：
10.1097/00001432-199806000-00009
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发表时间：
1998-06
影响因子：
3.9
通讯作者：
M. Jacobs;P. Young
中科院分区：
文献类型：
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作者：
M. Jacobs;P. Young
十年前，斯科特·霍尔斯特德发表了一篇开创性的评论，概述了登革热对科学的挑战。我们的综述总结了最近为应对这一挑战所做的努力，并讨论了基础研究的潜在实际意义。一个主要的长期目标是开发疫苗，目前正在推进几种不同的战略。对登革热的临床研究继续帮助医生在疾病管理中做出理性选择。
Ten years ago Scott Halstead published a seminal review outlining the challenge to science provided by dengue. Our review summarizes recent efforts to meet this challenge and discusses the potential practical implications of basic research. One major long-term goal is the development of a vaccine, and several different strategies are currently being advanced. Clinical studies on dengue continue to help physicians make rational choices in disease management.