Association of body mass index with respiratory symptoms and atopy: results from the European Community Respiratory Health Survey
Association of body mass index with respiratory symptoms and atopy: results from the European Community Respiratory Health Survey
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DOI：
10.1046/j.1365-2222.2002.01380.x
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发表时间：
2002-06-01
影响因子：
6.1
通讯作者：
Burney, P
中科院分区：
文献类型：
--
作者：
Jarvis, D;Chinn, S;Burney, P
背景有几个报告显示，肥胖的成年人比那些不肥胖的人报告更多的提示哮喘的呼吸道症状。目的确定体重指数与年轻人呼吸道症状和特应性的关系。方法收集来自欧洲共同体呼吸健康调查的15454名参与者的信息，这是一项多中心的年轻人横断面调查，结果体重指数大于30的男性和女性与体重在20-24.99之间的男性和女性相比，喘息伴呼吸急促的风险增加。（男性OR 1.85，95%置信区间1.41-2.42;女性OR 2.03，95%置信区间1.59-2.58）。其他症状提示或哮喘也观察到类似的关联，体重指数与“花粉热或鼻过敏”、屋尘螨特异性IgE无关。草或猫或总IgE在男性或女性。结论报告的体重指数与症状提示哮喘的协会是不太可能被解释为一个更高的风险过敏性肥胖。必须寻求其他解释。
Background There are several reports showing that obese adults report more respiratory symptoms suggestive of asthma than those who are not obese.Objective To determine the association of body mass index with respiratory symptoms and atopy in young adultsMethod Information collected from 15 454 participants in the European Community Respiratory Health Survey, a multicentre cross-sectional survey of young adults, was analysed to determine the association of body mass index with respiratory symptoms and atopy.Results Men and women with a body mass index of greater than 30 were at an increased risk of wheeze with shortness of breath compared with those with a body mass of 20-24.99 (OR in men 1.85, 95% confidence interval 1.41-2.42; OR in women 2.03, 95% confidence interval 1.59-2.58). Similar associations were observed for other symptoms suggestive or asthma, Body mass index was not associated with 'hayfever or nasal allergies', specific IgE to house dust mite. grass or cat or with total IgE in men or women.Conclusion Reported associations of body mass index with symptoms suggestive of asthma are unlikely to be explained by a higher risk of atopy in the obese. Alternative explanations must be sought.