IEDB-AR: immune epitope database-analysis resource in 2019
IEDB-AR: immune epitope database-analysis resource in 2019
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DOI：
10.1093/nar/gkz452
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发表时间：
2019-07-02
影响因子：
14.9
通讯作者：
Peters, Bjoern
中科院分区：
文献类型：
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作者：
Dhanda, Sandeep Kumar;Mahajan, Swapnil;Peters, Bjoern
免疫表位数据库分析资源（IEDB-AR，http://tools.iedb.org/）是 IEDB 的配套网站，提供专注于 B 和 T 细胞表位预测和分析的计算工具。所有工具都可以通过公共网站免费获得，许多工具还可以通过 REST API 和/或可下载的命令行工具获得。整个站点的虚拟机映像也可免费用于非商业用途，并且包含公共站点上的大部分工具。在这里，我们描述了 IEDB-AR 中提供的工具和功能，重点关注自 2012 年 NAR 网络服务器版上一份报告以来添加的 10 个新工具。此外，2012 年该网站上托管的许多工具已更新至最新版本，包括 NetMHC、NetMHCpan、BepiPred 和 DiscoTope。总体而言，此 IEDB-AR 更新为表位预测和分析提供了大量更新和新颖的功能。
The Immune Epitope Database Analysis Resource (IEDB-AR, http://tools.iedb.org/) is a companion website to the IEDB that provides computational tools focused on the prediction and analysis of B and T cell epitopes. All of the tools are freely available through the public website and many are also available through a REST API and/or a downloadable command-line tool. A virtual machine image of the entire site is also freely available for non-commercial use and contains most of the tools on the public site. Here, we describe the tools and functionalities that are available in the IEDB-AR, focusing on the 10 new tools that have been added since the last report in the 2012 NAR webserver edition. In addition, many of the tools that were already hosted on the site in 2012 have received updates to newest versions, including NetMHC, NetMHCpan, BepiPred and DiscoTope. Overall, this IEDB-AR update provides a substantial set of updated and novel features for epitope prediction and analysis.