NONINVASIVE TEMPERATURE IMAGING USING DIFFUSION MRI
NONINVASIVE TEMPERATURE IMAGING USING DIFFUSION MRI
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DOI：
10.1002/mrm.1910190224
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发表时间：
1991-06-01
影响因子：
3.3
通讯作者：
LEBIHAN, D
中科院分区：
文献类型：
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作者：
DELANNOY, J;CHEN, CN;LEBIHAN, D
采用热疗进行癌症治疗的有效性和安全性考虑需要在整个加热体积内进行准确的温度测量。我们报告使用分子扩散，其温度依赖性是众所周知的。建立了一个专用的热疗施加器，结合MRI梯度线圈和射频线圈。使用临床1.5‐T全身MRI系统，在聚丙烯酰胺凝胶体模上以1 × 2 mm像素大小获得扩散和衍生温度图像。发现使用1 cm 2感兴趣区域从这些图像中确定的温度与放置在凝胶内的热电偶和光纤探头记录的温度在0.2°范围内。出版社：Academic Press，Inc.
Efficacy and safety considerations for cancer therapy with hyperthermia require accurate temperature measurements throughout the heated volume. We report the use of molecular diffusion, whose temperature dependence is well known. A dedicated hyperthermia applicator was built, combining a MRI gradient coil and a rf coil. Diffusion and derived temperature images were obtained with a 1 × 2 mm pixel size on a polyacrylamide gel phantom using a clinical 1.5‐T whole body MRI system. Temperatures determined from these images using 1 cm2regions of interest were found to be within 0.2° of those recorded from the thermocouples and fiber‐optic probes placed inside the gel. © 1991 Academic Press, Inc.