Infant zygosity can be assigned by parental report questionnaire data.
Infant zygosity can be assigned by parental report questionnaire data.
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DOI：
10.1375/136905200320565391
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发表时间：
2000-09-01
期刊：
影响因子：
--
通讯作者：
Plomin, R
中科院分区：
文献类型：
--
作者：
Price, T S;Freeman, B;Plomin, R
一份寄给18个月大的双胞胎人群样本的家长报告问卷，在与通过多态性DNA标记的同一性确定的合子性进行验证时，在95%的案例中正确判定了合子性。该问卷在3岁时再次使用时同样准确，96%的儿童在两次测试中被判定为相同的合子性。这些结果证实了使用家长报告问卷数据来确定婴儿期合子性的可行性。
A parental report questionnaire posted to a population sample of 18-month-old twins correctly assigned zygosity in 95%of cases when validated against zygosity determined by identity of polymorphic DNA markers. The questionnaire was as accurate when readministered at 3 years of age, with 96% of children being assigned the same zygosity on both occasions. The results validate the use of parental report questionnaire data to determine zygosity in infancy.