COVID-19 prevalence, symptoms, and sociodemographic disparities in infection among insured pregnant women in Northern California.
COVID-19 prevalence, symptoms, and sociodemographic disparities in infection among insured pregnant women in Northern California.
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DOI：
10.1371/journal.pone.0256891
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发表时间：
2021
期刊：
影响因子：
3.7
通讯作者：
Croen LA
中科院分区：
文献类型：
--
作者：
Ames JL;Ferrara A;Avalos LA;Badon SE;Greenberg MB;Hedderson MM;Kuzniewicz MW;Qian Y;Young-Wolff KC;Zerbo O;Zhu Y;Croen LA
关于妊娠期新冠肺炎的研究主要集中在妊娠期因新冠肺炎或其他原因住院的妇女。人们对普通孕妇群体中的COVID-19知之甚少。描述以人口为基础的北加州孕妇样本中COVID-19的流行情况、症状、随之而来的医疗保健使用情况以及可能的COVID-19暴露来源。我们分析了2020年1月至2021年4月期间怀孕的北加州凯撒医疗机构19458名成员的数据，并对一项关于COVID-19检测、诊断、症状及其在COVID-19大流行期间经历的在线调查做出了回应。通过自我报告和电子健康记录（EHR）分别定义怀孕期间COVID-19的医学诊断。我们研究了COVID-19与社会人口因素、潜在合并症、COVID-19样症状的调查措施、随之而来的医疗保健利用以及可能的COVID-19暴露的关系。在19458名受访者中，自我报告的COVID-19粗流行率为2.5% (n = 494)，电子病历的粗流行率为1.4% （n = 276）。调整后，年龄<25岁的女性自我报告的COVID-19患病率高于年龄≥35岁的女性（患病率比[PR]， 1.75, 95% CI: 1.23, 2.49），西班牙裔女性高于白人女性（PR, 1.91, 95% CI: 1.53, 2.37）。在大流行期间个人或伴侣失业的女性中，自我报告的COVID-19患病率更高（相对危险度，1.23,95%可信区间：1.02,1.47），以及生活在社区贫困程度较高地区的女性中（相对危险度，1.74,95%可信区间：1.33,2.27）。我们没有观察到有和没有潜在合并症的女性自我报告的COVID-19差异。ehr记录的COVID-19结果相似。嗅觉或味觉丧失是COVID-19女性患者报告的一种独特而常见的症状（自我报告42.3%；电子健康档案54.0%）。在有症状的COVID-19女性中，约2%住院，71%进行了远程医疗访问，75%在家中隔离。超过三分之一的感染COVID-19的妇女报告没有接触过COVID-19患者。观察到的按社会人口和社会经济因素划分的COVID-19流行率差异凸显了育龄妇女之间的社会和健康不平等。感染COVID-19的女性报告了独特的症状和较低的住院频率。许多人没有意识到与COVID-19患者接触过。
Research on COVID-19 during pregnancy has mainly focused on women hospitalized for COVID-19 or other reasons during their pregnancy. Little is known about COVID-19 in the general population of pregnant women. To describe the prevalence of COVID-19, symptoms, consequent healthcare use, and possible sources of COVID-19 exposure among a population-based sample of pregnant women residing in Northern California. We analyzed data from 19,458 members of Kaiser Permanente Northern California who were pregnant between January 2020 and April 2021 and responded to an online survey about COVID-19 testing, diagnosis, symptoms, and their experiences during the COVID-19 pandemic. Medical diagnosis of COVID-19 during pregnancy was defined separately by self-report and by documentation in electronic health records (EHR). We examined relationships of COVID-19 with sociodemographic factors, underlying comorbidities, and survey measures of COVID-19-like symptoms, consequent healthcare utilization, and possible COVID-19 exposures. Among 19,458 respondents, the crude prevalence of COVID-19 was 2.5% (n = 494) according to self-report and 1.4% (n = 276) according to EHR. After adjustment, the prevalence of self-reported COVID-19 was higher among women aged <25 years compared with women aged ≥35 years (prevalence ratio [PR], 1.75, 95% CI: 1.23, 2.49) and among Hispanic women compared with White women (PR, 1.91, 95% CI: 1.53, 2.37). Prevalence of self-reported COVID-19 was higher among women affected by personal or partner job loss during the pandemic (PR, 1.23, 95% CI: 1.02, 1.47) and among women living in areas of high vs. low neighborhood deprivation (PR, 1.74, 95% CI: 1.33, 2.27). We did not observe differences in self-reported COVID-19 between women with and without underlying comorbidities. Results were similar for EHR-documented COVID-19. Loss of smell or taste was a unique and common symptom reported among women with COVID-19 (42.3% in self-reported; 54.0% in EHR-documented). Among women with symptomatic COVID-19, approximately 2% were hospitalized, 71% had a telehealth visit, and 75% quarantined at home. Over a third of women with COVID-19 reported no known exposure to someone with COVID-19. Observed COVID-19 prevalence differences by sociodemographic and socioeconomic factors underscore social and health inequities among reproductive-aged women. Women with COVID-19 reported unique symptoms and low frequency of hospitalization. Many were not aware of an exposure to someone with COVID-19.
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影响因子：
7.2
作者：
Afshar Y;Gaw SL;Flaherman VJ;Chambers BD;Krakow D;Berghella V;Shamshirsaz AA;Boatin AA;Aldrovandi G;Greiner A;Riley L;Boscardin WJ;Jamieson DJ;Jacoby VL;Pregnancy CoRonavIrus Outcomes RegIsTrY (PRIORITY) Study
通讯作者：
Pregnancy CoRonavIrus Outcomes RegIsTrY (PRIORITY) Study
DOI：
10.15585/mmwr.mm6938e1
发表时间：
2020-09-25
期刊：
MMWR. Morbidity and mortality weekly report
影响因子：
--
作者：
Delahoy MJ;Whitaker M;O'Halloran A;Chai SJ;Kirley PD;Alden N;Kawasaki B;Meek J;Yousey-Hindes K;Anderson EJ;Openo KP;Monroe ML;Ryan PA;Fox K;Kim S;Lynfield R;Siebman S;Davis SS;Sosin DM;Barney G;Muse A;Bennett NM;Felsen CB;Billing LM;Shiltz J;Sutton M;West N;Schaffner W;Talbot HK;George A;Spencer M;Ellington S;Galang RR;Gilboa SM;Tong VT;Piasecki A;Brammer L;Fry AM;Hall AJ;Wortham JM;Kim L;Garg S;COVID-NET Surveillance Team
通讯作者：
COVID-NET Surveillance Team
影响因子：
7.2
作者：
Goldfarb, Ilona Telefus;Clapp, Mark A.;Bryant, Allison S.
通讯作者：
Bryant, Allison S.
影响因子：
1.9
作者：
Flores, Katrina F.;Bandoli, Gretchen;Palmsten, Kristin
通讯作者：
Palmsten, Kristin
影响因子：
4.2
作者：
Cheng, Biheng;Jiang, Tao;Wang, Gaohua
通讯作者：
Wang, Gaohua