Multivariate analysis of energy dispersive X-ray diffraction data for the detection of illicit drugs in border control
Multivariate analysis of energy dispersive X-ray diffraction data for the detection of illicit drugs in border control
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DOI：
10.1186/s40163-016-0062-9
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发表时间：
2017-12-01
期刊：
影响因子：
6.1
通讯作者：
Speller, Robert
中科院分区：
文献类型：
--
作者：
Drakos, Ireneos;Kenny, Peter;Speller, Robert
已经测试了一种使用能量分散X射线衍射的系统，以检测通过邮政和快递服务进口到英国的包裹中隐藏的非法药物的存在。利用该系统对海洛因和常用切割剂的标准样品进行了衍射数据记录，建立了海洛因浓度与衍射谱之间的偏最小二乘回归模型。然后扫描含有各种结晶和无定形材料（包括二乙酰吗啡）的微粒，以获得多个局部衍射光谱并形成高光谱图像。校准模型用于预测整个包裹体积中的二乙酰吗啡浓度，并使二乙酰吗啡的存在和位置能够从浓度图的目视检查中确定。本研究首次展示了EDXRD系统在安全应用中从体积扫描生成真实的包裹的连续高光谱图像的潜力，并介绍了探索化学和材料识别中的高光谱图像分析的机会。然而，还必须做更多的工作，使该系统能够在边境管制行动中实施，办法是将程序时间缩短到业务要求，并证明该系统的可移植性。
A system using energy dispersive X-ray diffraction has been tested to detect the presence of illicit drugs concealed within parcels typical of those which are imported into the UK via postal and courier services. The system was used to record diffraction data from calibration samples of diamorphine (heroin) and common cutting agents and a partial least squares regression model was established between diamorphine concentration and diffraction spectra. Parcels containing various crystalline and amorphous materials, including diamorphine, were then scanned to obtain multiple localised diffraction spectra and to form a hyperspectral image. The calibration model was used for the prediction of diamorphine concentration throughout the volume of parcels and enabled the presence and location of diamorphine to be determined from the visual inspection of concentration maps. This research demonstrates for the first time the potential of an EDXRD system to generate continuous hyperspectral images of real parcels from volume scanning in security applications and introduces the opportunity to explore hyperspectral image analysis in chemical and material identification. However, more work must be done to make the system ready for implementation in border control operations by bringing down the procedure time to operational requirements and by proving the system's portability.