Epidemiological characteristics of pandemic influenza H1N1 2009 and seasonal influenza infection

Epidemiological characteristics of pandemic influenza H1N1 2009 and seasonal influenza infection
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DOI:
10.5694/j.1326-5377.2009.tb02723.x
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发表时间:
2009-08-03
影响因子:
11.4
通讯作者:
Smith, David
Smith, David
中科院分区:
医学2区
文献类型:
--
作者:
Kelly, Heath A.;Grant, Kristina A.;Smith, David

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在欧洲和美国的初始病例系列中,2009年H1N1大流行性流感感染患者的中位年龄报告为20-25岁。在对更多患者进行检测后,美国的这一年龄已降至13岁,但这可能反映了作为大流行应对措施的一部分,学龄儿童的检测有所增加。2007-2008年,西澳大利亚州和维多利亚州通过哨点监测发现的季节性甲型H1N1流感感染患者的中位年龄分别为18岁和22岁。对于2009年H1N1大流行性流感感染,在华盛顿州确定的前244名患者的中位年龄为22岁,维多利亚通过哨点监测发现的首批135名患者的中位年龄为21岁。对大流行性流感和季节性流感的流行病学特征进行其他比较是困难的,因为对季节性流感的实验室检测比大流行性流感少得多。监测数据表明,在西澳和维多利亚,流行性和季节性毒株共同传播,来自这两个州的最新数据表明,流行性流感越来越占主导地位。如果不断发展的流行性允许,我们应该利用对流行性流感进行的越来越多的检测,更多地了解实验室确认的季节性流感的真实的影响。MJA 2009; 191:146-149
The median age of patients with pandemic influenza H1N1 2009 infection was reported as 20-25 years in initial case series from Europe and the United States. This has been lowered to 13 years in the US after testing of more patients, but this may reflect differential increased testing of school-aged children as part of the pandemic response.The median age of patients with seasonal influenza A(H1N1) infection identified through sentinel surveillance in Western Australia and Victoria in 2007-2008 was 18 and 22 years, respectively. For pandernic influenza H1N1 2009 infection, the median age of the first 244 patients identified in WA was 22 years, and median age of the first 135 patients identified through sentinel surveillance in Victoria was 21 years.Other comparisons of the epidemiological features of pandernic and seasonal influenza are difficult because much less laboratory testing is done for seasonal than for pandernic influenza.While early surveillance data indicated co-circulation of both pandernic and seasonal strains in WA and Victoria, more recent data from both states indicate an increasing predominance of pandernic influenza.If the evolving pandernic allows, we should take advantage of the increased testing being conducted for pandemic influenza to learn more about the real impact of laboratory-confirmed seasonal influenza. MJA 2009; 191: 146-149