Gastric Reflux is a Significant Causative Factor of Tooth Erosion
Gastric Reflux is a Significant Causative Factor of Tooth Erosion
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DOI：
10.1177/0022034509336530
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发表时间：
2009-05-01
影响因子：
7.6
通讯作者：
Meurman, J. H.
中科院分区：
文献类型：
--
作者：
Holbrook, W. P.;Furuholm, J.;Meurman, J. H.
牙齿酸蚀是由饮食或胃酸引起的。这项研究的目的是检查牙齿酸蚀的位置和严重程度与引起因素的关系，并确定酸蚀的临床模式是否反映了主要的病因。这项研究涉及249名冰岛人，包括：详细的病史、临床口腔检查、唾液样本以及流速、pH值和缓冲能力的分析。91名患者通过胃镜检查、食道测压和24小时食道pH监测进行了反流评估。36.5%的患者报告有反流症状。8%的研究参与者测压结果异常，17.7%的人食道pH异常，21.3%的人24小时pH记录异常。幽门螺杆菌阳性率为3.6%。92%的患者唾液流量正常，但唾液缓冲不足(10.4%)与牙本质侵蚀有关(P<；0.05)。在被诊断为反流病(OR 2.772；P<；0.005)和每日饮用酸性饮料(OR 2.232；P<；0.005)之间发现显著的相关性。
Dental erosion is caused by dietary or gastric acid. This study aimed to examine the location and severity of tooth erosion with respect to causative factors, and to determine whether the clinical pattern of erosion reflected the dominant etiological factor. The study involved 249 Icelandic individuals and included: a detailed medical history; clinical oral examination; salivary sampling, and analysis for flow rate, pH, and buffering capacity. Reflux was assessed in 91 individuals by gastroscopy, esophageal manometry, and 24-hour esophageal-pH monitoring. Reflux symptoms were reported by 36.5% individuals. Manometry results were abnormal in 8% of study participants, abnormal esophageal pH in 17.7%, and a pathological 24-hour pH recording in 21.3%. 3.6% were positive for Helicobacter pylori. Normal salivary flow was found in 92%, but low salivary buffering (10.4%) was associated with erosion into dentin (P < 0.05). Significant associations were found between erosion and diagnosed reflux disease (OR 2.772; P < 0.005) and daily consumption of acidic drinks (OR 2.232; P < 0.005).