An enantioselective approach to (-)-platencin via catalytic asymmetric intramolecular cyclopropanation
An enantioselective approach to (-)-platencin via catalytic asymmetric intramolecular cyclopropanation
复制标题
DOI：
10.1016/j.tetlet.2010.07.088
复制
发表时间：
2010-09-22
影响因子：
1.8
通讯作者：
Nakada, Masahisa
中科院分区：
文献类型：
--
作者：
Hirai, Sho;Nakada, Masahisa
这封信描述了一种对映体选择性的方法来（-）-platencin。通过我们开发的高对映选择性催化不对称分子内环丙烷化反应（CAIMCP）制备了一种独特的功能化手性中间体，并成功地转化为Nicolaou全合成（-）-platencin的中间体。(C)2010爱思唯尔有限公司保留所有权利。
This Letter describes an enantioselective approach to (-)-platencin. A uniquely functionalized chiral intermediate, which was prepared via the highly enantioselective catalytic asymmetric intramolecular cyclopropanation (CAIMCP) that we have developed, was successfully transformed to Nicolaou's intermediate in his total synthesis of (-)-platencin. (C) 2010 Elsevier Ltd. All rights reserved.