Third ventricle enlargement and reduced electrodermal responsiveness.
Third ventricle enlargement and reduced electrodermal responsiveness.
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第三脑室扩大和皮肤电反应性降低。
DOI：
10.1111/j.1469-8986.1988.tb00978.x
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发表时间：
1988
期刊：
影响因子：
3.7
通讯作者：
Schulsinger,F
中科院分区：
文献类型：
--
作者：
Cannon,TD;Fuhrmann,M;Mednick,SA;Machon,RA;Parnas,J;Schulsinger,F
使用哥本哈根精神分裂症高危项目的子样本，我们研究了第三脑室扩大与阶段性皮电活动之间的关系，通过对定向，无条件，条件和概括刺激的反应幅度和频率进行测量。第三脑室扩大的受试者表现出显着的整体幅度和频率的反应，并显着降低响应水平，定向，条件反射和概括刺激。这些影响与精神病诊断和侧脑室扩大无关。讨论了所采用的萎缩指数以及皮电和脑电测量之间的18年时间间隔所造成的解释困难。这些结果是作为第三脑室扩大和自主神经系统活动减少之间的关联的初步迹象。
Using a subsample of subjects from the Copenhagen schizophrenia high‐risk project, we investigated the relationship between enlargement of the third ventricle and phasic electrodermal activity, as measured by amplitude and frequency of responses to orienting, unconditioned, conditioned, and generalization stimuli. Subjects with enlarged third ventricles evidenced significant overall reductions in amplitude and frequency of response, and significantly lower response levels to orienting, conditioned, and generalization stimuli. These effects were independent of psychiatric diagnosis and enlargement of the lateral cerebral ventricles. Difficulties in interpretation posed by the index of atrophy employed and by the 18‐year time interval between the electrodermal and brain measures are discussed. The results are presented as a preliminary indication of an association between third ventricle enlargement and reduced autonomic nervous system activity.