Physiological and performance responses to nicotinic-acid ingestion during exercise.
Physiological and performance responses to nicotinic-acid ingestion during exercise.
复制标题
运动期间摄入烟酸的生理和表现反应。
DOI：
10.1249/00005768-199507000-00015
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发表时间：
1995
影响因子：
4.1
通讯作者：
M. Horn
中科院分区：
文献类型：
--
作者：
Robert Murray;W. Bartoli;D. Eddy;M. Horn
本研究的目的是评估如何选定的生理和性能反应的影响时，血浆游离脂肪酸浓度在运动过程中的正常增加是由ingredient烟酸钝化。在四种情况下，10名受试者以68 +/-1%VO2peak骑自行车120分钟，然后进行定时3.5英里的性能任务。在运动期间，受试者每15分钟摄取ml.kg-1的四种饮料之一：1）水安慰剂（WP），2）WP + 280 mg烟酸1 -1（WP + NA），3）6%碳水化合物-电解质饮料（CE），和4）CE + NA。摄入烟酸（WP + NA和CE + NA）减弱了与WP和CE相关的FFA升高;事实上，NA摄入有效地阻止了FFA升高至静息值以上。NA喂养的低FFA水平与整个运动过程中人类生长激素浓度增加3至6倍有关。CE（10.7 min）的平均执行时间显著短于WP（12.2 min）和WP + NA（12.8 min），但与CE + NA（11.4 min）无差异。结果表明，抑制FFA的正常上升会改变运动对激素的反应，并降低进行高强度运动的能力。
The purpose of this study was to assess how selected physiological and performance responses are affected when the normal increase in plasma free fatty acid concentration during exercise is blunted by ingesting nicotinic acid. On four occasions, 10 subjects cycled at 68 +/- 1% VO2peak for 120 min followed by a timed 3.5-mile performance task. Every 15 min during exercise, subjects ingested 3.5 ml.kg LBM-1 of one of four beverages: 1) water placebo (WP), 2) WP + 280 mg nicotinic acid.l-1 (WP + NA), 3) 6% carbohydrate-electrolyte beverage (CE), and 4) CE + NA. Ingestion of nicotinic acid (WP + NA and CE + NA) blunted the rise in FFA associated with WP and CE; in fact, NA ingestion effectively prevented FFA from rising above rest values. The low FFA levels with NA feeding were associated with a 3- to 6-fold increase in concentrations of human growth hormone throughout exercise. The mean performance time for CE (10.7 min) was significantly less than for WP (12.2 min) and WP + NA (12.8 min), but did not differ from CE + NA (11.4 min). The results indicate that blunting the normal rise in FFA alters the hormonal response to exercise and reduces the capacity to perform high-intensity exercise.